Defrol 1000 IU (Tablet)
Unit Price: ৳ 6.00 (5 x 10: ৳ 300.00)
Strip Price: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cholecalciferol vitamin d3 |
| Company | Acme laboratories ltd |
| Also available as |
Indications
- Prevention of rickets
- Treating osteoporosis
- Boosting immunity
- Preventing pre-eclampsia during pregnancy
Pharmacology
- Calcitriol binds to Vitamin D receptors
- Vitamin D3 absorption in small intestine
- Metabolism to 25-hydroxy Vitamin D3
- Storage in tissues like fat and muscle
Dosage & Administration
- 40000 IU once weekly for 7 weeks for adults with Vitamin D3 deficiency
- 20000 IU every 4 weeks for prevention of Vitamin D3 deficiency in adults
- 1000 IU (1-2 tablets) daily for adults using film-coated tablet
Interaction
- Interference with absorption and metabolism by certain drugs
- Increased need for Vitamin D3 due to corticosteroids
Contraindications
- Vitamin D3 is contraindicated in diseases associated with hypercalcaemia
- Known hypersensitivity to Vitamin D3
Side Effects
- Anorexia
- Nausea & vomiting
- Diarrhea
- Weight loss
- Headache
- Thirst
- Raised concentrations of calcium and phosphate in plasma and urine
Pregnancy & Lactation
- Safe use of doses up to 4000 IU during pregnancy
- Excretion in breast milk
- Higher dose may be required in Vitamin D3 deficient pregnant women
Precautions & Warnings
- Monitoring plasma-calcium concentration
- Consulting a health care practitioner before supplementing for specific conditions
Use in Special Populations
- Safety & efficacy not established in children under 12 years
Overdose Effects
- Hypervitaminosis D
Therapeutic Class
- Vitamin in bone formation
- Vitamin-D preparations
Storage Conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children