D-Cap 40000 IU (Capsule)
Unit Price: ৳ 35.00 (1 x 10: ৳ 350.00)
Strip Price: ৳ 350.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cholecalciferol vitamin d3 |
| Company | Drug international ltd |
| Also available as |
Indications
- Treatment of Vitamin D3 deficiency
- Prevention of Vitamin D3 deficiency
- Essential for healthy bones and teeth
- Preventing rickets, osteomalacia, and osteoporosis
- Preventing pre-eclampsia during pregnancy and breastfeeding
- Immunity booster
Pharmacology
- Active form: Calcitriol
- Binding to Vitamin D receptors (VDRs)
- Absorbed in the small intestine
- Metabolised to 25-hydroxy Vitamin D3
- Half-life of about 50 days
- Second hydroxylation in the kidney
- Increases the absorption of calcium
- Stored in fat and muscle
- Elimination via faeces and urine
Dosage & Administration
- Adult dosage - for Vitamin D3 deficiency and maintenance therapy
- Children dosage - for Vitamin D3 deficiency and prevention
- Dosage forms: capsule, film-coated tablet, oroflash/chewable tablets, syrup, injection
- Daily dosage for different forms
- Dosage for specific therapy for osteoporosis
- Dosage for different age groups and specific conditions
Interaction
- Drugs causing Vitamin D3 deficiencies
- Drugs interfering with absorption and metabolism of Vitamin D3
- Drugs increasing the need for Vitamin D3
Contraindications
- Contraindicated in diseases associated with hypercalcaemia
- Contraindicated in patients with known hypersensitivity to Vitamin D3
- Contraindicated if evidence of Vitamin D3 toxicity
Side Effects
- Symptoms: anorexia, lassitude, nausea & vomiting, diarrhea, constipation, weight loss, polyuria, sweating, headache, thirst, vertigo
- Raised concentrations of calcium and phosphate in plasma and urine
Pregnancy & Lactation
- Safe use up to 4000 IU during pregnancy
- Excreted in breast milk
- Need for higher dose during deficiency
- Exogenous vitamin D3 dosage for breast-fed child
Precautions & Warnings
- Monitoring plasma-calcium concentration
- Consultation for patients using Digoxin and Thiazide Diuretics
- Consultation for patients with liver or kidney disease, primary hyperthyroidism, lymphoma, tuberculosis, and granulomatous disease
Use in Special Populations
- Safety & efficacy not established in children under 12 years
Overdose Effects
- Hypervitaminosis D
Therapeutic Class
- Vitamin in bone formation
- Vitamin-D preparations
Storage Conditions
- Keep below 30° C temperature
- Protected from light & moisture
- Keep out of reach of children