D-Cap 20000 IU (Capsule)
Unit Price: ৳ 20.00 (1 x 10: ৳ 200.00)
Strip Price: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cholecalciferol vitamin d3 |
| Company | Drug international ltd |
| Also available as |
Indications
- Vitamin D3 deficiency
- Limited exposure to sunlight
- Diet deficient in Vitamin D3
- Healthy bones and teeth
- Preventing rickets
- Osteomalacia and osteoporosis
- Pre-eclampsia during pregnancy
- Boosting immunity
Pharmacology
- Active form of Vitamin D3: Calcitriol
- Effect by binding to Vitamin D receptors
- Calcitriol half-life: 50 days
- Absorption in small intestine
- Metabolism to 25-hydroxy Vitamin D3 (Calcidiol)
- Second hydroxylation to 1,25-dihydroxy Vitamin D3 (Calcitriol)
- Storage in tissues such as fat and muscle
- Elimination via feces and urine
Dosage & Administration
- Capsule for adults and children
- Film-coated tablet
- Oroflash or chewable tablets
- Syrup for patients with risk of Cholecalciferol deficiency
- Injection for prevention and deficiency
- Different doses for different age groups and conditions
Interaction
- Drugs causing Vitamin D3 deficiencies
- Interference with absorption and metabolism of Vitamin D3
- Drugs like Magnesium containing Antacids, Digoxin, Thiazide Diuretics, Cholestyramine, Cholistipol, Phenytoin, Phenobarbital, Orlistat, Mineral Oil, Corticosteroids (e.g., Prednisolone)
Contraindications
- Diseases associated with hypercalcemia
- Known hypersensitivity to Vitamin D3
- Evidence of Vitamin D3 toxicity
Side Effects
- Symptoms including anorexia, lassitude, nausea & vomiting, diarrhea, constipation, weight loss, polyuria, sweating, headache, thirst, vertigo, raised concentrations of calcium and phosphate in plasma and urine
Pregnancy & Lactation
- Safe use of doses up to 4000 IU during pregnancy
- Recommended daily intake for pregnant women: 400 IU
- Excretion of Vitamin D3 and its metabolites in breast milk
- Importance of following medical practitioner's advice
Precautions & Warnings
- Monitoring plasma-calcium concentration
- Consultation before supplementing with Vitamin D3 in certain conditions or with specific drugs
Use in Special Populations
- Safety & efficacy not established in children under 12 years
Overdose Effects
- Hypervitaminosis D
Therapeutic Class
- Vitamin in bone formation
- Vitamin-D preparations
Storage Conditions
- Keep below 30°C temperature
- Protected from light and moisture
- Keep out of the reach of children