Prevas 20 mg (Capsule (Enteric Coated))
Unit Price: ৳ 5.00 (5 x 10: ৳ 250.00)
Strip Price: ৳ 50.00
Medicine Details
Category | Details |
---|---|
Generic | Omeprazole |
Company | General pharmaceuticals ltd |
Also available as |
Indications
- Gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer
- As prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease
- Long-term management of acid reflux disease
- Acid-related dyspepsia
- Severe ulcerating reflux esophagitis
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome
- Helicobacter pylori-induced peptic ulcer
Pharmacology
- Inhibitor of gastric acid secretion
- Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
- Onset of the antisecretory effect occurs within one hour
- Maximum effect occurs within two hours
- Inhibition of secretion lasts up to 72 hours
Dosage
- Dosage available for benign gastric and duodenal ulcer
- Dosage available for NSAID-associated duodenal or gastric ulcer
- Dosage available for gastro-esophageal reflux disease
- Dosage available for long-term management of acid reflux disease
- Dosage available for acid-related dyspepsia
- Dosage available for prophylaxis of acid aspiration
- Dosage available for Zollinger-Ellison syndrome
- Dosage available for Helicobacter pylori eradication regimen in peptic ulcer disease
- Pediatric use in severe ulcerating reflux esophagitis
Administration
- Direction for use of IV Injection
- Direction for use of IV Infusion
- IV injection should be given as a slow intravenous injection
- IV infusion should be given as an intravenous infusion over a period of 20-30 minutes or more
Interaction
- Decreased intragastric acidity
- Absorption of ketoconazole may be reduced
- Metabolized in the liver through cytochrome P450
- Plasma concentrations of Prevas and clarithromycin are increased during concomitant administration
- No evidence of an interaction with piroxicam, diclofenac, or naproxen
Contraindications
- Known hypersensitivity to Omeprazole
- Possibility of malignancy when gastric ulcer is suspected
Side Effects
- Skin rash, urticaria and pruritus
- Photosensitivity, bullous eruption, erythema multiforme, angioedema and alopecia
- Diarrhea and headache
- Gastrointestinal reactions like constipation, nausea/vomiting, flatulence and abdominal pain
- Dry mouth, stomatitis and candidiasis
- Paraesthesia
- Dizziness, light headedness
- Reversible mental confusion, agitation, depression and hallucinations
- Arthritic and myalgic symptoms
- Blurred vision, taste disturbance, peripheral oedema
Pregnancy & Lactation
- No adverse effects of Omeprazole on pregnancy or on the health of the fetus/newborn child
- Omeprazole can be used during pregnancy
Precautions & Warnings
- Avoid concomitant use of clopidogrel and Prevas
- Proton pump inhibitor (PPI) therapy may be associated with an increased risk for osteoporosis-related fractures
- Atrophic gastritis has been noted occasionally in gastric corpus biopsies from patients treated long-term with Prevas
- Concomitant use of PPIs with methotrexate may lead to methotrexate toxicities
Therapeutic Class
- Proton Pump Inhibitor
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
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