Clarimycin 500 mg (Tablet)
Unit Price: ৳ 45.00 (10's pack: ৳ 450.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Clarithromycin |
| Company | Amico laboratories ltd |
Indications
- Acute bacterial exacerbation of chronic bronchitis in adults
- Acute maxillary sinusitis
- Community-acquired pneumonia
- Pharyngitis or tonsillitis
- Uncomplicated skin and skin structure infections
- Acute otitis media in pediatric patients
- Treatment and prophylaxis of disseminated mycobacterial infections
- Helicobacter pylori infection and duodenal ulcer disease in adults
Pharmacological Actions
- Inhibition of microsomal protein synthesis
- Binding to the donor site on the 50S subunit
- Preventing translocation to the site
- Activity against most Gram-positive bacteria and Chlamydia
- Acid stability
- Twice the activity against H. influenzae compared to Erythromycin
- Resistance in most species of Gram-negative bacteria
Dosage and Administration
- Recommended dosages for different conditions in adults
- Combination dosing regimens for H. pylori infection
- Recommended dosages for pediatric patients
- Administration in patients with renal and hepatic impairment
Drug Interaction
- Contraindication with specific medications
- Not recommended to use with specific antiarrhythmics drugs
Contraindications
- Known hypersensitivity to clarithromycin, erythromycin, or macrolide antibacterial drugs
- History of cholestatic jaundice or hepatic dysfunction associated with prior use of clarithromycin
Side Effects
- Nausea
- Vomiting
- Diarrhoea
- Abdominal pain
- Stomatitis
- Glossitis
- Headache
- Allergic reactions
- Taste perversion
- Transient central nervous system side effects
Pregnancy and Lactation
- Usage in neonates and children
- Recommendation regarding breastfeeding
Precautions and Warnings
- Discontinuation if severe acute hypersensitivity reactions occur
- Avoidance in patients with known QT prolongation or receiving specific drugs
- Discontinuation if signs and symptoms of hepatitis occur
Use in Special Populations
- Established safety and effectiveness in pediatric patients
- Limited safety data in specific age groups
Overdose Effects
- Expected gastrointestinal symptoms with large ingestion
- Reported symptoms in a specific overdose case
Therapeutic Class
Macrolides
Storage Conditions
Requirements for storage and shelf life