Trunac 1.2%+0.025% (Topical Gel)

15 gm tube: ৳ 140.00

Medicine Details

Category Details
Generic Clindamycin tretinoin
Company Pharmasia limited

Indications

  • Topical treatment of Acne vulgaris

Pharmacology

  • Combination of lincosamide antibiotic Clindamycin phosphate and retinoid Tretinoin
  • Clindamycin binds with the 50s ribosomal subunit
  • Prevention of elongation of peptide chain
  • Interference with peptidyl transfer
  • Suppressing bacterial protein synthesis
  • Inhibition of Propionibacterium acne activity
  • Tretinoin decreases cohesiveness of follicular epithelial cells
  • Increases follicular cell turnover
  • Brings comedones out

Dosage & Administration

  • Apply before sleep
  • Wash face with mild soap and water before application
  • Pat skin dry before application
  • Apply sunscreen in the morning
  • Avoid washing face more than 2-3 times a day
  • Safety and effectiveness not established for children below 12 years

Interaction

  • Concomitant use of potentially irritating topical products should be approached with caution
  • Decreased activity when used concomitantly with Erythromycin
  • Avoid concomitant use with Erythromycin
  • Increased activity of neuromuscular medicine with concomitant use

Contraindications

  • Hypersensitivity to Clindamycin or Tretinoin or any other component of the Gel

Side Effects

  • Erythema
  • Scaling
  • Nasopharyngitis
  • Dry skin
  • Cough
  • Sinusitis
  • Diarrhea

Pregnancy & Lactation

  • Exercise special caution while applying to a nursing mother

Precautions & Warnings

  • Do not apply to eyes, nose, ear, lips, cut, burn, or other infections
  • Keep away from sunlight after application

Therapeutic Class

  • Topical antibiotic & retinoid preparations

Storage Conditions

  • Keep below 25°C temperature
  • Keep away from light & moisture
  • Keep out of the reach of children

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