Dermastin (0.5 mg+5 mg+1 Lac IU)/gm (Ointment)

15 gm tube: ৳ 70.00

Medicine Details

Category	Details
Generic	Clobetasol propionate neomycin sulphate nystatin
Company	Ibn sina pharmaceuticals ltd
Also available as	Dermastin 05 mg cream

Indications

Short courses treatment of recalcitrant eczemas
Neurodermatoses
Psoriasis (excluding widespread plaque psoriasis)
Other inflammatory conditions

Pharmacology

Corticosteroid
Antibiotic
Antifungal
Anti-inflammatory activity
Vasoconstriction
Decrease in collagen synthesis
Protein synthesis inhibition
Change in membrane permeability

Dosage & Administration

Apply sparingly once or twice daily
Enhanced anti-inflammatory effect with occlusion
Not recommended for more than 7 days without medical supervision
Not recommended for use in neonates and infants

Interaction

Intensify and prolong respiratory depressant effects
Minimal systemic exposure expected
Unlikely hazardous interactions

Contraindications

Rosacea
Acne vulgaris
Perioral dermatitis
Primary cutaneous viral infection
Hypersensitivity

Side Effects

Hypercortisolism with prolonged use
Local atrophic changes in the skin
Pigmentation changes
Hypertrichosis
Thinning of the skin
Dilatation of superficial blood vessels

Pregnancy & Lactation

Theoretical risk of foetal toxicity
Not recommended in pregnancy and lactation
Safety not established in lactating mothers

Precautions & Warnings

Avoid long-term continuous topical therapy
Care needed when applied to eyelids
Avoid entry into the eye
Adrenal suppression in infants and children
Wash affected eye with water if entered

Overdose Effects

Acute overdosage unlikely
Features of hypercortisolism with chronic overdosage
Discontinue gradually in case of overdose problems

Therapeutic Class

Corticosteroid / Antibiotic / Antifungal

Storage Conditions

Store below 25°C
Do not freeze
Keep out of reach of children

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