Dermastin (0.5 mg+5 mg+1 Lac IU)/gm (Ointment)
15 gm tube: ৳ 70.00
Medicine Details
Category | Details |
---|---|
Generic | Clobetasol propionate neomycin sulphate nystatin |
Company | Ibn sina pharmaceuticals ltd |
Also available as |
Indications
- Short courses treatment of recalcitrant eczemas
- Neurodermatoses
- Psoriasis (excluding widespread plaque psoriasis)
- Other inflammatory conditions
Pharmacology
- Corticosteroid
- Antibiotic
- Antifungal
- Anti-inflammatory activity
- Vasoconstriction
- Decrease in collagen synthesis
- Protein synthesis inhibition
- Change in membrane permeability
Dosage & Administration
- Apply sparingly once or twice daily
- Enhanced anti-inflammatory effect with occlusion
- Not recommended for more than 7 days without medical supervision
- Not recommended for use in neonates and infants
Interaction
- Intensify and prolong respiratory depressant effects
- Minimal systemic exposure expected
- Unlikely hazardous interactions
Contraindications
- Rosacea
- Acne vulgaris
- Perioral dermatitis
- Primary cutaneous viral infection
- Hypersensitivity
Side Effects
- Hypercortisolism with prolonged use
- Local atrophic changes in the skin
- Pigmentation changes
- Hypertrichosis
- Thinning of the skin
- Dilatation of superficial blood vessels
Pregnancy & Lactation
- Theoretical risk of foetal toxicity
- Not recommended in pregnancy and lactation
- Safety not established in lactating mothers
Precautions & Warnings
- Avoid long-term continuous topical therapy
- Care needed when applied to eyelids
- Avoid entry into the eye
- Adrenal suppression in infants and children
- Wash affected eye with water if entered
Overdose Effects
- Acute overdosage unlikely
- Features of hypercortisolism with chronic overdosage
- Discontinue gradually in case of overdose problems
Therapeutic Class
- Corticosteroid / Antibiotic / Antifungal
Storage Conditions
- Store below 25°C
- Do not freeze
- Keep out of reach of children
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- Dermatas N (0.5 mg+5 mg+1 Lac IU)/gm (Cream) - kumudini-pharma-ltd