Sypam 2 mg (Tablet)
Unit Price: ৳ 10.00 (50's pack: ৳ 500.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Clonazepam |
| Company | Asiatic laboratories ltd |
| Also available as |
Indications
- Treatment of panic disorder with or without agoraphobia
- Treatment of Lennox-Gastaut Syndrome
- Treatment of akinetic and myoclonic seizures
- Treatment of absence seizures (petit mal)
Pharmacology
- Anticonvulsive effects
- Sedative effects
- Muscle relaxing effects
- Anxiolytic effects
- Enhancement of GABAergic neurotransmission
Dosage & Administration
- Usual initial dose for adults with seizure disorders: 1.5 mg/day divided into three doses
- Usual initial dose for adults with panic disorder: 0.25 mg given in two divided doses
- Usual initial dose for pediatric patients: 0.01-0.03 mg/kg/day up to 0.05 mg/kg/day
Interactions
- No significant alteration of phenytoin, carbamazepine, or phenobarbital pharmacokinetics
Contraindications
- History of hypersensitivity to benzodiazepines
- Clinical or biochemical evidence of significant liver disease
- Acute narrow angle glaucoma
Side Effects
- CNS depression
- Drowsiness
- Ataxia
- Behavior problems
- Abnormal eye movements
- Aphonia
- Coma
- Tremor
- Vertigo
- Depression
- Amnesia
- Hallucinations
- Increased libido
- Insomnia
- Psychosis
- Palpitations
Pregnancy & Lactation
- Potential for producing congenital malformations
- Use only if potential benefits outweigh risks to the fetus
- Administration during pregnancy may cause irregularities in the heartbeat of the unborn child
- Passage of active ingredient into maternal milk
Precautions & Warnings
- Increased incidence of generalized tonic-clonic seizures in patients with multiple seizure disorders
- Concomitant use with valproic acid may produce absence status
Use in Special Populations
- Increased production of saliva and bronchial secretion in infants and small children
- Greater pharmacologic effects in elderly patients
- No dose adjustment required in patients with renal impairment
- Reduced clearance in liver cirrhosis
Overdose Effects
- Drowsiness
- Ataxia
- Dysarthria
- Nystagmus
- Areflexia
- Apnoea
- Hypotension
- Cardiorespiratory depression
- Coma
Therapeutic Class
- Adjunct anti-epileptic drugs
- Benzodiazepine hypnotics
Reconstitution
- Dilution with water for injection prior to intravenous administration
- Dilution for intravenous infusion in specified ratios
- Use of intramuscular route only in exceptional cases
Storage Conditions
- Dry place away from light and heat
Chemical Structure
- Molecular Formula: C15H10ClN3O3