Clonaben 2 mg (Tablet)

Unit Price: ৳ 11.00 (5 x 10: ৳ 550.00)
Strip Price: ৳ 110.00

Medicine Details

Title

  • Clonaben 2 mg Tablet

Categories

  • Medicine
  • Pharmaceuticals

Indications

  • Treatment of panic disorder with or without agoraphobia
  • Adjunct in the treatment of Lennox-Gastaut Syndrome, akinetic and myoclonic seizures
  • Patients with absence seizures who have failed to respond to succinimides

Pharmacology

  • Exhibits anticonvulsive, sedative, muscle relaxing and anxiolytic effects
  • Enhances GABAergic neurotransmission at inhibitory synapses
  • Suppresses various types of paroxysmal activity including spike and wave discharge in absences seizures

DosageAndAdministration

  • Initial dose for adults with seizure disorders should not exceed 1.5 mg/day
  • Initial dose for adults with panic disorder is 0.25 mg given in two divided doses
  • Dosage may be adjusted based on patient response
  • Maximum recommended daily dose is 20 mg

Interaction

  • Does not alter the pharmacokinetics of phenytoin, carbamazepine, or phenobarbital

Contraindications

  • History of hypersensitivity to benzodiazepines
  • Clinical or biochemical evidence of significant liver disease
  • Acute narrow angle glaucoma

SideEffects

  • CNS depression
  • Drowsiness
  • Ataxia
  • Behavior problems
  • Abnormal eye movements
  • Coma
  • Tremor
  • Vertigo
  • Depression
  • Amnesia
  • Hallucinations
  • Increased libido
  • Insomnia
  • Psychosis
  • Palpitations

PregnancyAndLactation

  • Potential for producing congenital malformations
  • Anticonvulsant drugs may act as teratogens
  • Caution advised during pregnancy and lactation

PrecautionsAndWarnings

  • May increase the incidence or precipitate the onset of generalized tonic-clonic seizures in certain patient groups
  • Concomitant use with valproic acid may produce absence status

UseInSpecialPopulations

  • Special attention required in infants and small children due to increased production of saliva and bronchial secretion
  • Benzodiazepine pharmacologic effects appear to be greater in elderly patients
  • No dose adjustment required in patients with renal impairment

OverdoseEffects

  • Symptoms of overdose include drowsiness, ataxia, dysarthria, nystagmus
  • May lead to coma, hypotension, cardiorespiratory depression
  • Benzodiazepines increase the effects of other central nervous system depressants, including alcohol

TherapeuticClass

  • Adjunct anti-epileptic drugs
  • Benzodiazepine hypnotics

Reconstitution

  • Instructions for slow intravenous injection, intravenous infusion, and intramuscular injection

StorageConditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

ChemicalStructure

  • Molecular Formula: C15H10ClN3O3
  • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-284-clonazepam-chemical-structure-S6GmKrvYS03ZYjOTAtig.svg

CommonQuestions

  • Information about the medication as a sleeping pill
  • Long-term usage guidance
  • Withdrawal symptoms upon stopping medication
  • Early symptoms of suicidal thoughts and actions
  • Potential impact on weight and memory
  • Harmful effects of overdose
  • Interactions with other medications

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