Cloron 1 mg (Tablet)

Unit Price: ৳ 8.00 (5 x 10: ৳ 400.00)
Strip Price: ৳ 80.00

Medicine Details

Indications

  • Treatment of panic disorder with or without agoraphobia
  • Treatment of Lennox-Gastaut Syndrome (petit mal variant), akinetic and myoclonic seizures
  • Adjunct in the treatment of absence seizures (petit mal)
  • Long-term use effectiveness not studied
  • Physician's periodic reevaluation for long-term use
  • GABAergic neurotransmission enhancement for anticonvulsive effects

Pharmacology

  • Anticonvulsive effects
  • Sedative effects
  • Muscle relaxing effects
  • Anxiolytic effects
  • Enhancement of GABAergic neurotransmission
  • Effect on serotonin
  • Suppression of paroxysmal activity
  • Beneficial effects in generalized and focal epilepsies

Dosage & Administration

  • Initial dose for adults with seizure disorders
  • Initial dose for adults with panic disorder
  • Dosage adjustment based on response
  • Max recommended daily dose
  • Dose for pediatric patients
  • Oral and injection administration

Interaction

  • No alteration of pharmacokinetics of phenytoin, carbamazepine, or phenobarbital
  • Effect on the metabolism of other drugs not investigated

Contraindications

  • History of hypersensitivity to benzodiazepines
  • Clinical or biochemical evidence of significant liver disease
  • Contraindicated in acute narrow angle glaucoma

Side Effects

  • CNS depression
  • Drowsiness
  • Ataxia
  • Behavior problems
  • Abnormal eye movements
  • Coma
  • Tremor
  • Depression
  • Psychosis
  • Palpitations

Pregnancy & Lactation

  • Potential for producing congenital malformations
  • Evidence of anticonvulsant drugs as teratogens
  • Administration during pregnancy if compelling indication
  • Administration during labor effects on the unborn child

Precautions & Warnings

  • Increased incidence of generalized tonic-clonic seizures
  • Concomitant use with valproic acid
  • Increased pharmacologic effects in elderly patients
  • Renal impairment and hepatic impairment effects

Use in Special Populations

  • Increased saliva and bronchial secretion in infants and small children
  • Greater pharmacologic effects in elderly patients
  • No dose adjustment required in renal impairment
  • Influence of hepatic impairment on pharmacokinetics

Overdose Effects

  • Drowsiness
  • Ataxia
  • Dysarthria
  • Nystagmus
  • Cardiorespiratory depression
  • Coma
  • Increased frequency of seizures

Therapeutic Class

Adjunct anti-epileptic drugs, Benzodiazepine hypnotics

Reconstitution

  • Dilution for IV injection
  • Dilution for intravenous infusion
  • Stable mixtures
  • Infusion bag materials
  • Precautions for infusing

Storage Conditions

Dry place away from light and heat, Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C15H10ClN3O3
  • Chemical Structure: Image reference provided

Common Questions

  • Sleeping pill usage: Not recommended for sleeping
  • Duration of usage: As per doctor's advice
  • Withdrawal symptoms: Difficulty in sleeping, changes in mood, increased sweating and more
  • Early symptoms of suicidal thoughts: Sudden changes in mood, behaviors, thoughts, or feelings
  • Effect on memory: Complaints of partial recall of the recent past
  • Harmful effects of overdose: Sleepiness, change in speech, confusion, abnormalities in eye movement

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