Disopan 1 mg/ml (IM/IV Injection)

1 mg vial: ৳ 150.00

Medicine Details

Category Details
Generic Clonazepam
Company Incepta pharmaceuticals ltd
Also available as
Disopan 05 mg tablet Disopan 2 mg tablet Disopan 1 mg tablet

Title

  • Disopan 1 mg/ml Injection

Categories

  • Medicine
  • Pharmaceuticals
  • Benzodiazepines
  • Anticonvulsants
  • Anxiolytics

Description

  • Disopan is indicated for the treatment of panic disorder, with or without agoraphobia.
  • It is also indicated in the treatment of Lennox-Gastaut Syndrome, akinetic and myoclonic seizures.
  • Clonazepam exhibits anticonvulsive, sedative, muscle relaxing, and anxiolytic effects.
  • It should not be used in patients with a history of hypersensitivity to benzodiazepines or significant liver disease.
  • Common side effects of Disopan include CNS depression, drowsiness, ataxia, behavior problems, abnormal eye movements, aphonia, coma, tremor, vertigo, and more.
  • Use of Disopan during pregnancy and lactation should be carefully considered, as it may pose risks to the fetus and nursing infant.
  • Disopan may interact with other drugs, and precautions should be taken in patients with seizure disorders, open angle glaucoma, or respiratory disease.

Dimensions

  • N/A

Color Options

  • Clear liquid form for injection

Functions

  • Treatment of panic disorder
  • Anticonvulsive effects
  • Sedative effects
  • Muscle relaxing effects
  • Anxiolytic effects

Materials

  • Active ingredient: Clonazepam
  • Chemical Structure: C15H10ClN3O3
  • Molecular Formula: C15H10ClN3O3

Technical Specifications

  • Dosage for adults with panic disorder: 0.25 mg initial dose, with a target dose of 1 mg/day
  • Maximum recommended daily dose: 20 mg
  • Dosage for pediatric patients: 0.01-0.03 mg/kg/day, not to exceed 0.05 mg/kg/day
  • Injection: Administered by slow IV injection or IV infusion, with specific dosages for adults and children

Design Elements

  • N/A

Usability Features

  • Requires careful monitoring during administration
  • Prescribed dosages must be strictly adhered to
  • Should be stored in a dry place away from light and heat
  • Keep out of the reach of children

Indications

  • Treatment of panic disorder with or without agoraphobia
  • Treatment of Lennox-Gastaut Syndrome, akinetic and myoclonic seizures

Mode of Action

  • Enhancement of GABAergic neurotransmission
  • Effect on serotonin
  • Suppression of paroxysmal activity including spike and wave discharge in absences seizures

Interaction

  • No significant alteration of the pharmacokinetics of certain drugs observed
  • Effects on other drug metabolism not systematically studied

Contraindications

  • Hypersensitivity to benzodiazepines
  • Significant liver disease
  • Acute narrow angle glaucoma

Side Effects

  • CNS depression
  • Drowsiness
  • Ataxia
  • Behavior problems
  • Abnormal eye movements
  • Aphonia
  • Coma
  • Tremor
  • Vertigo

Pregnancy & Lactation

  • Potential teratogenic effects in pregnancy
  • Small amounts found in breast milk
  • Benefits vs. risks must be carefully assessed

Precautions & Warnings

  • May increase incidence or precipitate onset of generalized tonic-clonic seizures in certain patients
  • Concomitant use with valproic acid may produce absence status
  • Increased pharmacologic effects in elderly patients

Use in Special Populations

  • Increased saliva and bronchial secretion in infants and small children
  • Greater pharmacologic effects in elderly patients
  • Unaffected by renal impairment
  • Possible reduction in clearance in liver cirrhosis

Overdose Effects

  • Drowsiness
  • Ataxia
  • Dysarthria
  • Nystagmus
  • Areflexia
  • Apnoea
  • Hypotension
  • Cardiorespiratory depression
  • Coma

Therapeutic Class

  • Adjunct anti-epileptic drugs
  • Benzodiazepine hypnotics

Reconstitution

  • Instructions for slow intravenous injection
  • Instructions for intravenous infusion
  • Warnings about using intramuscular injection only in exceptional cases

Storage Conditions

  • Recommended storage in a dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C15H10ClN3O3
  • Chemical Structure: Image provided

Commonly Asked Questions

  • FAQs about usage, side effects, drug interactions, and precautions

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