Propin 20 mg (Capsule (Enteric Coated))
Unit Price: ৳ 5.01 (40's pack: ৳ 200.40)
Medicine Details
Category | Details |
---|---|
Generic | Omeprazole |
Company | Hallmark pharmaceuticals ltd |
Also available as |
Indications
- Treatment of gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer treatment
- Prophylaxis in patients with history of NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease treatment
- Long-term management of acid reflux disease
- Treatment of acid-related dyspepsia
- Severe ulcerating reflux esophagitis treatment
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome treatment
- Helicobacter pylori-induced peptic ulcer treatment
Pharmacology
- Inhibitor of gastric acid secretion
- Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
- Onset of antisecretory effect within one hour
- Maximum antisecretory effect within two hours
- Inhibition of secretion lasts up to 72 hours
Dosage
- Oral administration for various conditions and maintenance doses
- IV Injection for prophylaxis of acid aspiration and specific syndromes
- Different dosages for severe ulcerating reflux esophagitis in paediatric use
Administration
- Direction for use of IV Injection
- Direction for use of IV Infusion
- Preparation of IV infusion solution
- Instructions for slow intravenous injection
Interaction
- Absorption of ketoconazole may be reduced during treatment
- Metabolised in the liver through cytochrome P450
- Delay in elimination of diazepam, phenytoin, and warfarin
- Monitoring of patients receiving warfarin or phenytoin
- Plasma concentrations may be increased during concomitant administration
Contraindications
- Known hypersensitivity to omeprazole
- Exclusion of malignancy possibility before treatment
Side Effects
- Mild and reversible adverse reactions
- Reported skin rash, urticaria, and pruritus
- Diarrhoea and headache reported
- Gastrointestinal reactions included constipation, nausea/vomiting
- Dizziness, light headedness, and feeling faint associated with treatment
- Reversible mental confusion, agitation, depression, and hallucinations
Pregnancy & Lactation
- No adverse effects of omeprazole on pregnancy or fetus
- Use during pregnancy indicated
- No information available on passage into breast milk
- Breast-feeding discontinuation if essential use of omeprazole
Precautions & Warnings
- Avoid concomitant use of clopidogrel and omeprazole
- Possible increased risk for osteoporosis-related fractures
- Atrophic gastritis noted occasionally in patients treated long-term with omeprazole
Therapeutic Class
- Proton Pump Inhibitor
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
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