SB-Clopido 75 mg (Tablet)
Unit Price: ৳ 12.00 (30's pack: ৳ 360.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Clopidogrel bisulphate |
| Company | Sunman birdem pharma ltd |
Indications
- Reduce rate of myocardial infarction
- Reduce rate of stroke
- Non-ST-segment elevation ACS
- ST-elevation myocardial infarction
- Peripheral Arterial Disease
Pharmacology
- Prodrug
- Inhibits platelet activation
- Irreversible binding to P2Y12 receptors
- Dose-dependent inhibition of platelet aggregation
Dosage & Administration
- 300 mg oral loading dose
- 75 mg once daily orally
- Oral use with or without food
Interaction
- Increased risk of bleeding with NSAIDs, warfarin, SSRIs, and SNRIs
- Avoid concomitant use with CYP2C19 inhibitors
- Increased plasma concentrations of Repaglinide with concomitant use
Contraindications
- Hypersensitivity to the drug substance
- Active pathological bleeding
Side Effects
- Common: Bleeding, Diarrhoea, gastrointestinal discomfort, haemorrhage, Skin reactions
- Rare: Acquired haemophilia, anaemia, angioedema, arthralgia, arthritis, bone marrow disorders
Pregnancy & Lactation
- Use during pregnancy only if clearly needed
- Unknown excretion in human breast milk
- Decision regarding nursing and drug discontinuation
Precautions & Warnings
- Impairment by genetic variations in CYP2C19
- Risk of bleeding and need for hemostasis restoration
- Discontinuation and cardiovascular events risk
- Thrombotic Thrombocytopenic Purpura (TTP) risk
- Hypersensitivity reactions
Use in Special Populations
- Safety and effectiveness in pediatric populations not established
- No dosage adjustment necessary in elderly patients
Overdose Effects
- May lead to bleeding complications
- Platelet transfusion for clotting restoration
Therapeutic Class
- Anti-platelet drugs
Storage Conditions
- Keep below 30°C temperature in a dry place
- Protected from light
- Do not freeze
- Keep out of the reach of children