Nilfun 1% (Cream)
10 gm tube: ৳ 35.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clotrimazole topical |
| Company | Team pharmaceuticals ltd |
Indications
- Treatment of dermatomycoses due to dermatophytes
- Treatment of dermatomycoses due to yeasts
- Treatment of dermatomycoses due to moulds and other fungi
- Treatment of skin diseases showing superinfections with fungi
- Treatment of interdigital mycoses (e.g. athlete's foot)
- Treatment of paronychias associated with nail mycoses
- Treatment of mycoses in skin folds
- Treatment of Candida vulvitis
- Treatment of Candida balanitis
- Treatment of Pityriasis versicolor
- Treatment of erythrasma
Description
- Broad-spectrum antifungal agent
- Treats dermal infections caused by various species of pathogenic dermatophytes, yeasts, moulds, and bacteroids
- Active against certain gram-positive bacteria especially Staphylococci and Tricomonas
- Alters the permeability of fungal cell walls
- Inhibition of ergosterol synthesis
- Damages the permeability barrier in the cell membrane of fungi
- Depletion of intracellular calcium
- Induces inhibition of lanosterol 14-demethylase
- Inhibits sarcoplasmic reticulum Ca2+ ATPase
- Blocks calcium-dependent potassium channels and voltage-dependent calcium channels
Pharmacology
- Damages the permeability barrier in the cell membrane of fungi
- Inhibits ergosterol biosynthesis
- Inhibition of lanosterol 14-demethylase
- Inhibits sarcoplasmic reticulum Ca2+ ATPase
- Depletes intracellular calcium
- Blocks calcium-dependent potassium channels and voltage-dependent calcium channels
Dosage & Administration
- Thinly apply 2-3 times daily to infected sites
- Rub in gently
- Duration of treatment varies based on disease extent and localization
- Recommended duration of treatment for specific conditions
- Prevent relapse in fungal infection of the feet
- Odorless, washable off, does not stain clothing
- Apply topical solution sparingly to affected areas and rub in gently
Interaction
- No interaction information available
Contraindications
- Hypersensitivity to Clotrimazole
Side Effects
- Well tolerated when applied topically
- No systemic effects observed with external application
- Possible local irritation or burning sensation in very few cases
Pregnancy & Lactation
- Recommended to be used in pregnancy only when considered necessary by the physician
Therapeutic Class
- Drugs for subcutaneous and mycoses
- Topical Antifungal preparations
Storage Conditions
- Keep below 25°C temperature
- Keep away from light & moisture
- Keep out of the reach of children