Seclo 20 mg (Capsule (Enteric Coated))
Unit Price: ৳ 6.00 (12 x 10: ৳ 720.00)
Strip Price: ৳ 60.00
Medicine Details
Category | Details |
---|---|
Generic | Omeprazole |
Company | Square pharmaceuticals plc |
Also available as |
Indications
- Gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer
- As prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease
- Long-term management of acid reflux disease
- Acid-related dyspepsia
- Severe ulcerating reflux esophagitis
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome
- Helicobacter pylori-induced peptic ulcer
Pharmacology
- Inhibitor of gastric acid secretion
- Blocker of hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
- Onset of antisecretory effect within one hour
- Maximum effect occurring within two hours
- Inhibition of secretion lasting up to 72 hours
- Gradual return of secretory activity over 3 to 5 days after discontinuation
Dosage
- Dosage for benign gastric and duodenal ulcer
- Dosage for NSAID-associated duodenal or gastric ulcer
- Dosage for gastro-esophageal reflux disease
- Dosage for long-term management of acid reflux disease
- Dosage for acid-related dyspepsia
- Dosage for prophylaxis of acid aspiration
- Dosage for Zollinger-Ellison syndrome
- Helicobacter pylori eradication regimen dosage
- Pediatric dosage for severe ulcerating reflux esophagitis
Administration
- Direction for use of IV Injection
- Direction for use of IV Infusion
- Preparation of IV injection solution
- Preparation of IV infusion solution
- Time duration for IV infusion
- Instructions for use of IV infusion
Interaction
- Decreased intragastric acidity affecting ketoconazole absorption
- Metabolism through cytochrome P450
- Potential delay in elimination of diazepam, phenytoin, and warfarin
- Recommendation for monitoring patients receiving warfarin or phenytoin
- Plasma concentration increase during concomitant administration with clarithromycin
- Lack of evidence of interaction with various drugs
- Increased bioavailability of digoxin with simultaneous treatment
Contraindications
- Known hypersensitivity to omeprazole
- Exclusion of malignancy before treatment initiation in suspected gastric ulcer
Side Effects
- Mild and reversible adverse reactions
- Reported skin reactions (rash, urticaria, pruritus)
- Photosensitivity, bullous eruption, erythema multiforme, angioedema, alopecia in isolated cases
- Gastrointestinal reactions (diarrhea, headache, constipation, nausea, vomiting, flatulence, abdominal pain)
- Other reported reactions (dry mouth, stomatitis, candidiasis, paraesthesia, dizziness, somnolence, insomnia, vertigo)
Pregnancy & Lactation
- No adverse effects on pregnancy or fetus/newborn child in prospective epidemiological studies
- Safe use during pregnancy
- Lack of information on passage into breast milk and effects on the neonate
- Recommendation to discontinue breastfeeding if essential use is considered
Precautions & Warnings
- Avoid concomitant use of clopidogrel and Seclo
- Potential association of PPI therapy with increased risk for osteoporosis-related fractures
Therapeutic Class
- Proton Pump Inhibitor
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
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