Cyphos 200 mg/vial (IV Infusion)
200 mg vial: ৳ 150.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cyclophosphamide |
| Company | Drug international ltd |
| Also available as |
Indications
- Malignant lymphomas treatment
- Hodgkin's disease treatment
- Leukemias treatment
- Neuroblastoma treatment
- Ovarian adenocarcinoma treatment
- Retinoblastoma treatment
- Breast carcinoma treatment
- Nephrotic syndrome treatment
- Nonmalignant disease treatment
Pharmacology
- Biotransformation in the liver
- Alkylating metabolites production
- Interference with malignant cell growth
- DNA cross-linking mechanism
Dosage & Administration
- Intravenous dosing regimen
- Oral dosing regimen
- Adjustable dosages based on antitumor activity
- Leukocyte count monitoring
- Effects on total white blood cell count
Interaction
- Metabolism rate alteration by phenobarbital
- Concurrent drug actions
- Cholinesterase activity inhibition
- Effects on succinylcholine chloride
Contraindications
- Severely depressed bone marrow function
- Hypersensitivity reactions
Side Effects
- Nausea and vomiting
- Anorexia
- Skin rash
- Alopecia
- Leukopenia
- Thrombocytopenia
- Renal tubular necrosis
- Interstitial pneumonitis
Pregnancy & Lactation
- Pregnancy Category D
- Excretion in breast milk
- Tumorigenicity potential
Precautions & Warnings
- Leukopenia monitoring
- Thrombocytopenia monitoring
- Impaired hepatic function consideration
- Impaired renal function consideration
- Tumor cell infiltration awareness
Use in Special Populations
- Pediatric use safety profile
- Geriatric use caution
- Elderly patient dose selection
Overdose Effects
- Supportive measures management
- Concurrent infection treatment
- Cardiac toxicity treatment
Therapeutic Class
- Cytotoxic Chemotherapy
Storage Conditions
- Temperature restrictions
- Protection from light and moisture