S-Ome 20 mg (Tablet (Enteric Coated))

Title

• S-Ome 20 mg Tablet

Categories

• Medicine
• Healthcare
• Pharmaceutical

Indications

• Relief from chronic heartburn symptoms
• Healing of erosive esophagitis
• Maintenance of healing of erosive esophagitis
• Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease
• Zollinger-Ellison Syndrome
• Treatment for acid-related Dyspepsia
• Treatment for Duodenal & Gastric ulcers

Pharmacology

• Proton pump inhibitor
• Suppresses gastric acid secretion
• First single optical isomer of proton pump inhibitor
• Good bioavailability
• Extensively metabolized in the liver
• Excretion mainly through urine and faeces

DosageForms

• Oral capsule
• Oral suspension
• IV Injection
• IV infusion

DosageInstructions

• Oral administration before meals
• Dosage varies for different indications
• IV administration for specific conditions

Interaction

• Metabolized by CYP2C19 and CYP3A4
• Potential interference with certain drugs
• No significant interactions with phenytoin, warfarin, quinidine, clarithromycin, or amoxicillin

Contraindications

• Hypersensitivity to any of the formulation

SideEffects

• Headache
• Diarrhoea
• Nausea
• Flatulence
• Abdominal pain
• Constipation
• Dry mouth

PregnancyAndLactation

• No adequate and well-controlled studies in pregnant women
• No excretion data in breast milk
• Discontinuation of breastfeeding if essential

PrecautionsAndWarnings

• Symptomatic response does not preclude presence of gastric malignancy
• Specific instructions for patients with swallowing difficulties
• Use of antacids possible during treatment

SpecialPopulations

• Safety and effectiveness not established in paediatric patients
• No significant differences in safety and efficacy observed between elderly and younger individuals
• No dosage adjustment for mild to moderate hepatic insufficiency
• Expected pharmacokinetics in patients with renal impairment

OverdoseEffects

• Lethal dose in rats
• Expected symptoms of acute toxicity
• No specific antidote
• Symptomatic and supportive treatment recommended

StorageConditions

• Store at temperature not exceeding 30°C
• Protect from light and moisture
• Keep out of reach of children

ChemicalStructure

• Molecular Formula: C17H19N3O3S

CommonQuestions

• Use in treatment of GERD, ulcers, and other conditions related to excess stomach acid
• Possible side effects and their common occurrence
• Pregnancy and breastfeeding considerations
• Onset of action and quick tips for usage

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