Glycema 5 mg (Tablet)
Unit Price: ৳ 20.00 (3 x 10: ৳ 600.00)
Strip Price: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Dapagliflozin propanediol |
| Company | Aci limited |
| Also available as |
Indications
- Improves glycemic control in adults with type 2 diabetes mellitus
Pharmacology
- Inhibitor of Sodium-glucose co-transporter 2 (SGLT2)
- Increases urinary glucose excretion
Dosage & Administration
- Recommended starting dose of 5 mg once daily for adults
- Can be increased to 10 mg once daily for additional glycemic control
- Assessment of renal function recommended prior to initiation
- Not established for children and adolescents
Interaction
- May interact with diuretics, insulin, insulin secretagogues, antihypertensives, pioglitazone, agents affecting renal function, GLP-1 agonists, valsartan, rifampin, mefenamic acid
Contraindications
- Known hypersensitivity to Dapagliflozin or excipients
- Severe renal impairment, end-stage renal diseases, or dialysis
Side Effects
- Hypotension
- Ketoacidosis
- Acute kidney injury
- Hypoglycemia with concomitant use with insulin
- Genital mycotic infections
- Increases in low-density lipoprotein cholesterol (LDL-C)
- Nasopharyngitis
- Urinary tract infection
- Bladder cancer
Pregnancy & Lactation
- Pregnancy category C
- Should be used during pregnancy only if potential benefit justifies potential risk to the fetus
- Not recommended during lactation
Precautions & Warnings
- Assess volume status and correct hypovolemia before initiating
- Monitor for signs and symptoms of hypotension during therapy
- Monitor renal function during therapy
- Consider lower dose of insulin or insulin secretagogue to reduce risk of hypoglycemia
- Caution in patients with history of bladder cancer
Therapeutic Class
- Sodium-glucose Cotransporter-2 (SGLT2) Inhibitors
Storage Conditions
- Store in a cool (below 30°C) & dry place protected from light
- Keep away from the reach of children