Glycema 10 mg (Tablet)
Unit Price: ৳ 30.00 (2 x 10: ৳ 600.00)
Strip Price: ৳ 300.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Dapagliflozin propanediol |
| Company | Aci limited |
| Also available as |
Indications
- Adjunct to diet and exercise
- Improves glycemic control
- Type 2 diabetes mellitus
Pharmacology
- Inhibitor of Sodium-glucose co-transporter 2 (SGLT2)
- Reduces reabsorption of filtered glucose
- Increases urinary glucose excretion
Dosage & Administration
- Recommended starting dose of 5 mg once daily
- Dose can be increased to 10 mg once daily
- Assessment of renal function recommended
- Discontinued in case of low eGFR
Interaction
- Potential interaction with diuretics
- May cause hypoglycemia with insulin or sulphonylureas
- Interaction with antihypertensives, pioglitazone, and others
Contraindications
- Known hypersensitivity to Dapagliflozin or excipients
- Severe renal impairment
- End-stage renal diseases
- Patients on dialysis
Side Effects
- Hypotension
- Ketoacidosis
- Acute kidney injury
- Hypoglycemia
- Genital mycotic infections
- Increases in LDL-C
- Urinary tract infection
- Bladder cancer
Pregnancy & Lactation
- Pregnancy category C
- Use during pregnancy only if potential benefit justifies risk to fetus
- Should not be used during lactation
Precautions & Warnings
- Assess volume status before initiation
- Monitor hypovolemia
- Monitor renal function during therapy
- Consider lower insulin dose to reduce hypoglycemia risk
- Use with caution in patients with history of bladder cancer
Therapeutic Class
- Sodium-glucose Cotransporter-2 (SGLT2) Inhibitors
Storage Conditions
- Store in a cool, dry place
- Protect from light
- Keep away from the reach of children