Daxetin 60 mg (Tablet)
Unit Price: ৳ 50.00 (2 x 4: ৳ 400.00)
Strip Price: ৳ 200.00
Medicine Details
Category | Details |
---|---|
Generic | Dapoxetine hydrochloride |
Company | Aci limited |
Also available as |
Indications
- Treatment of premature ejaculation in men 18 to 64 years of age
- Ejaculation with minimal sexual stimulation before, on, or shortly after penetration
- Marked personal distress or interpersonal difficulty as a consequence of PE
- Poor control over ejaculation
Pharmacology
- Inhibition of neuronal reuptake of serotonin
- Potentiation of neurotransmitter's action
- Rapid absorption with maximum plasma concentrations occurring 1-2 hours after intake
- Absolute bioavailability is 42%
- Extensive metabolism to multiple metabolites primarily through various biotransformational pathways
- Rapid distribution with a mean steady state volume of distribution of 162 L
- Terminal half-life is approximately 19 hours
Dosage & Administration
- Recommended starting dose for adult men is 30 mg
- Maximum recommended dosing frequency is once every 24 hours
- Dose may be increased to the maximum recommended dose of 60 mg if 30 mg is insufficient
- Not recommended for use in individuals below 18 years of age
- Caution advised in patients with mild or moderate renal impairment
- Contraindicated in patients with moderate and severe hepatic impairment
Interaction
- Concomitant administration with CNS active medicinal products
- Prescribed with caution in patients who use PDE5 inhibitors
- Prescribed with caution in patients who use alpha adrenergic receptor antagonists
- Caution advised when used in patients taking Warfarin chronically
- Concomitant use of alcohol could increase the chance or severity of adverse reactions
Contraindications
- Known hypersensitivity to Dapoxetine Hydrochloride
- Significant pathological cardiac conditions
- Concomitant treatment with monoamine oxidase inhibitors
- Concomitant treatment with serotonin reuptake inhibitors
- Not recommended within 14 days of discontinuing treatment with serotonergic medicinal/herbal products
Side Effects
- Nausea
- Dizziness
- Dry mouth
- Headache
- Diarrhea
- Insomnia
- Low rates of sexual dysfunction
Pregnancy & Lactation
- Not indicated for use by women
- Not known if excreted through human breast milk
Precautions & Warnings
- Not to be used in combination with recreational drugs
- Avoid alcohol while taking Dapoxetine
- Patients could experience syncope at any time during their treatment
- An orthostatic test should be performed before initiating therapy
- Caution advised in patients taking Dapoxetine with medicinal products known to affect platelet function
- Prescribed with caution in patients who use PDE5 inhibitors
- Not recommended in patients with a history of bleeding or coagulation disorders
Overdose Effects
- No case of overdose reported
- Symptoms of overdose with SSRIs include serotonin-mediated adverse reactions
- No evidence of withdrawal syndrome
Therapeutic Class
- Drugs for Erectile Dysfunction
Storage Conditions
- Store below 30°C
- Protect from light and moisture
- Keep out of reach of children