Defzort 6 mg (Tablet)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Deflazacort |
| Company | Aci limited |
| Also available as |
Indications
- Anaphylaxis
- Asthma
- Rheumatoid arthritis
- Juvenile chronic arthritis
- Systemic lupus erythematosus
- Dermatomyositis
- Mixed connective tissue disease
- Polyartritis nodosa
- Sarcoidosis
- Pemphigus
- Bullous pemphigoid
- Pyoderma gangrenosum
- Minimal change nephrotic syndrome
- Acute interstitial nephritis
- Rheumatic carditis
- Ulcerative colitis
- Crohn's disease
- Uveitis
- Optic neuritis
- Autoimmune haemolytic anaemia
- Idiopathic thrombocytopenic purpura
- Acute and lymphatic leukaemia
- Malignant lymphoma
- Multiple myeloma
- Immune suppression in transplantation
Pharmacology
Anti-inflammatory action, Inhibition of Phospholipase A2 enzyme, Immunosuppressive action
Dosage & Administration
- Adult dosage range: 3-120 mg/day
- Children dosage range: 0.25-1.5 mg/kg/day
- Dosage varies with different conditions and patient age
- Caution with abrupt withdrawal in certain patients
Interaction
Metabolized in the liver, Maintenance dose adjustment with liver enzyme inducers/inhibitors
Contraindications
Hypersensitivity to ingredients, Live virus immunization
Side Effects
- GI disturbances
- Musculoskeletal effects
- Endocrine effects
- Neuropsychiatric effects
- Ophthalmic effects
- Fluid and electrolyte disturbances
- Increased susceptibility to infection
- Impaired healing
- Hypersensitivity reactions
- Skin atrophy
- Striae
- Telangiectasia
- Acne
- Thromboembolism
Pregnancy & Lactation
Crosses placenta, Potential risk of intrauterine growth retardation, Excretion in breast milk, Adrenal suppression in infants with higher maternal doses
Precautions & Warnings
- Patient monitoring for cardiac disease, hypertension, thromboembolic disorders
- Caution in gastritis, oesophagitis, diverticulitis, ulcerative colitis
- Special caution in diabetes mellitus, osteoporosis, myasthenia gravis, renal insufficiency
- Monitoring in emotional instability, psychotic tendency, epilepsy, myopathy, liver failure, hypothyroidism, cirrhosis, ocular herpes simplex
Use in Special Populations
- Hepatic impairment: Monitor and adjust dose carefully
- Renal impairment: Normal precautions
- Elderly: Common adverse effects may have serious consequences
Therapeutic Class
- Glucocorticoids
Storage Conditions
Store below 25°C, Protect from light and moisture, Keep out of the reach of children