Cortimax 6 mg (Tablet)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Deflazacort |
| Company | Acme laboratories ltd |
| Also available as |
Indications
- Anaphylaxis, asthma, severe hypersensitivity reactions
- Rheumatoid arthritis, juvenile chronic arthritis, polymyalgia rheumatica
- Systemic lupus erythematosus, dermatomyositis, mixed connective tissue disease (other than systemic sclerosis), polyartritis nodosa, sarcoidosis
- Pemphigus, bullous pemphigoid, pyoderma gangrenosum
- Minimal change nephrotic syndrome, acute interstitial nephritis
- Rheumatic carditis
- Ulcerative colitis, Crohn's disease
- Uveitis, optic neuritis
- Autoimmune haemolytic anaemia, idiopathic thrombocytopenic purpura
- Acute and lymphatic leukaemia, malignant lymphoma, multiple myeloma
- Immune suppression in transplantation
Pharmacology
Anti-inflammatory action by inhibiting Phospholipase A2 enzyme, immunosuppressive action by decreasing release of certain immune system chemicals
Dosage & Administration
- Up to 120 mg/day for acute disorders
- 3-18 mg/day for most conditions in adults
- 0.25-1.5 mg/kg/day for children
- Gradual dose reduction for patients on more than physiological doses for greater than 3 weeks
Interaction
Metabolized in the liver, maintenance dose adjustment needed with liver enzyme inducers or inhibitors
Contraindications
Hypersensitivity to any of the ingredients, patients receiving live virus immunization
Side Effects
- GI disturbances
- Musculoskeletal effects
- Endocrine effects
- Neuropsychiatric effects
- Ophthalmic effects
- Fluid and electrolyte disturbances
- Susceptibility to infection
- Impaired healing
- Hypersensitivity reactions
- Skin atrophy, striae, telangiectasia, acne
- Myocardial rupture following recent MI
- Thromboembolism
Pregnancy & Lactation
- Corticosteroids may increase risk of intrauterine growth retardation
- Excreted in breast milk, higher doses may cause systemic effects in the infant
Precautions & Warnings
- Special caution for patients with cardiac disease, congestive heart failure, hypertension, thromboembolic disorders
- Caution in patients with gastritis, oesophagitis, diverticulitis, ulcerative colitis, impending perforation, abscess, pyogenic infections, or active or latent peptic ulcer
- Monitoring and precautions for patients with diabetes mellitus, family history, osteoporosis, myasthenia gravis, renal insufficiency, emotional instability, psychotic tendency, epilepsy, corticosteroid-induced myopathy, liver failure, hypothyroidism, cirrhosis, and ocular herpes simplex
Use in Special Populations
- Hepatic Impairment: Monitor and adjust dose carefully
- Renal Impairment: No special precautions
- Elderly: Common adverse effects may have more serious consequences
Therapeutic Class
Glucocorticoids
Storage Conditions
Cool (below 25°C) and dry place, protected from light & moisture, keep out of the reach of children