Xalcort 6 mg/5 ml (Oral Suspension)
60 ml bottle: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Deflazacort |
| Company | Beacon pharmaceuticals plc |
| Also available as |
Indications
- Anaphylaxis
- Asthma
- Severe hypersensitivity reactions
- Rheumatoid arthritis
- Juvenile chronic arthritis
- Polymyalgia rheumatica
- Systemic lupus erythematosus
- Dermatomyositis
- Mixed connective tissue disease
- Polyartritis nodosa
- Sarcoidosis
- Pemphigus
- Bullous pemphigoid
- Pyoderma gangrenosum
- Minimal change nephrotic syndrome
- Acute interstitial nephritis
- Rheumatic carditis
- Ulcerative colitis
- Crohn's disease
- Uveitis
- Optic neuritis
- Autoimmune haemolytic anaemia
- Idiopathic thrombocytopenic purpura
- Acute leukaemia
- Malignant lymphoma
- Multiple myeloma
- Immune suppression in transplantation
Pharmacology
- Anti-inflammatory action
- Inhibition of Phospholipase A2 enzyme
- Prostaglandin synthesis inhibition
- Immunosuppressive action
- Decreased release of immune system chemicals
Dosage & Administration
- Adult dosage range: 3-120 mg/day
- Maintenance doses for various conditions
- Pediatric dosage range: 0.25-1.5 mg/kg/day
- Alternate day administration
Interaction
- Metabolized in the liver
- Recommended dose adjustments with liver enzyme inducers and inhibitors
Contraindications
- Hypersensitivity to ingredients
- Patients receiving live virus immunization
Side Effects
- GI disturbances
- Musculoskeletal effects
- Endocrine effects
- Neuropsychiatric effects
- Ophthalmic effects
- Fluid and electrolyte disturbances
- Increased susceptibility to infection
- Impaired healing
- Hypersensitivity reactions
- Skin atrophy
- Striae
- Telangiectasia
- Acne
- Myocardial rupture
- Thromboembolism
Pregnancy & Lactation
- Placental transfer of medication
- Increased risk of intrauterine growth retardation
- Excretion in breast milk
- Potential adrenal suppression in infants
Precautions & Warnings
- Special caution for specific clinical conditions
- Necessity of patient monitoring
- Effects on cardiac disease and heart failure
- Potential salt and water retention
- Increased excretion of potassium
- Necessity of dietary salt restriction and potassium supplementation
- Precautions for GI disorders
- Potential risk of perforation, abscess or pyogenic infections
- Caution for diabetes mellitus
- Osteoporosis risk
- Myasthenia gravis caution
- Renal insufficiency precautions
- Caution with emotional instability or psychotic tendency
- Risk of corticosteroid-induced myopathy
- Caution for liver failure
- Effects on hypothyroidism and cirrhosis
- Ocular herpes simplex precautions
Use in Special Populations
- Dose monitoring in hepatic impairment
- No special precautions for renal impairment
- No special precautions for elderly patients
Therapeutic Class
- Glucocorticoids
Storage Conditions
- Store below 25°C
- Store in a dry place
- Protected from light and moisture
- Keep out of the reach of children