Dezert 6 mg (Tablet)
Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Deflazacort |
| Company | Globe pharmaceuticals ltd |
Indications
- Anaphylaxis
- Asthma
- Rheumatoid arthritis
- Juvenile chronic arthritis
- Systemic lupus erythematosus
- Dermatomyositis
- Mixed connective tissue disease
- Polyartritis nodosa
- Sarcoidosis
- Pemphigus
- Bullous pemphigoid
- Pyoderma gangrenosum
- Minimal change nephrotic syndrome
- Acute interstitial nephritis
- Rheumatic carditis
- Ulcerative colitis
- Crohn's disease
- Uveitis
- Optic neuritis
- Autoimmune hemolytic anemia
- Idiopathic thrombocytopenic purpura
- Acute and lymphatic leukemia
- Malignant lymphoma
- Multiple myeloma
- Immune suppression in transplantation
Pharmacology
- Anti-inflammatory action
- Inhibition of Phospholipase A2
- Prostaglandin synthesis
- Immunosuppressive action
- Inhibition of certain immune system chemicals release
Dosage & Administration
- Adult dosage range: up to 120 mg/day for acute disorders
- Adult maintenance doses range: 3-18 mg/day
- Children dosage range: 0.25-1.5 mg/kg/day
- Alternate day administration may be appropriate
- Dose reduction for patients on long-term corticosteroids
- Special dosage for specific conditions like rheumatoid arthritis, bronchial asthma, juvenile chronic arthritis, and nephrotic syndrome
Interaction
- Metabolism in liver
- Recommended maintenance dose adjustment with liver enzyme inducers and inhibitors like rifampicin, ketoconazole
Contraindications
- Hypersensitivity to the product or any of its ingredients
- Patients receiving live virus immunization
Side Effects
- GI disturbances
- Musculoskeletal issues
- Endocrine effects
- Neuropsychiatric symptoms
- Ophthalmic complications
- Fluid and electrolyte disturbances
- Increased susceptibility to infection
- Impaired healing
- Hypersensitivity reactions
- Skin atrophy
- Telangiectasia
- Acne
- Thromboembolism
Pregnancy & Lactation
- Potential risk in prolonged/repeated use during pregnancy
- Excretion in breast milk
- Infant adrenal suppression risk
Precautions & Warnings
- Caution in cardiac disease, congestive heart failure, and hypertension
- Additional precautions for gastritis, oesophagitis, diverticulitis, and ulcerative colitis
- Monitoring for diabetes mellitus, osteoporosis, myasthenia gravis, and renal insufficiency
- Special considerations for emotional instability, psychotic tendency, epilepsy, and corticosteroid-induced myopathy
- Caution in liver failure, hypothyroidism, cirrhosis, and ocular herpes simplex
Use in Special Populations
- Dose monitoring in hepatic impairment
- Standard precautions in renally impaired patients
- No specific precautions for elderly patients
Therapeutic Class
- Glucocorticoids
Storage Conditions
- Cool and dry storage (below 25°C)
- Protection from light and moisture
- Keep out of the reach of children