Deflazit 24 mg (Tablet)
Unit Price: ৳ 30.00 (2 x 10: ৳ 600.00)
Strip Price: ৳ 300.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Deflazacort |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Title and Categories
- Deflazit
- Medicine
- Pharmaceuticals
- Health Care
Dimensions
- N/A
Color Options
- N/A
Functions
- Anti-inflammatory
- Immunosuppressive
Materials
- N/A
Technical Specifications
- Inhibits Phospholipase A2 enzyme
- Metabolized in the liver
Design Elements
- N/A
Usability Features
- Indicated for various conditions like anaphylaxis, asthma, arthritis, lupus, nephrotic syndrome, immune suppression
- Dosage varies based on condition, age, and severity
- Requires caution in patients with specific clinical conditions
- Storage: cool and dry place, protected from light and moisture
Indications
- Anaphylaxis
- Asthma
- Rheumatoid arthritis
- Juvenile chronic arthritis
- Polymyalgia rheumatica
- Lupus erythematosus
- Dermatomyositis
- Connective tissue diseases
- Polyartritis nodosa
- Sarcoidosis
- Pemphigus
- Bullous pemphigoid
- Pyoderma gangrenosum
- Nephrotic syndrome
- Interstitial nephritis
- Rheumatic carditis
- Ulcerative colitis
- Crohn's disease
- Uveitis
- Optic neuritis
- Autoimmune hematologic disorders
- Leukemia
- Lymphoma
- Multiple myeloma
- Transplantation
Dosage and Administration
- Adult dosage range: Up to 120 mg/day for acute disorders, maintenance doses 3-18 mg/day for most conditions
- Children dosage: 0.25-1.5 mg/kg/day, dose varies based on condition
- Deflazacort withdrawal protocol for patients with prolonged use of corticosteroids
Pharmacology
- Provides anti-inflammatory action by inhibiting Phospholipase A2 enzyme
- Immunosuppressive action by decreasing release of certain immune system chemicals
Interaction
- Metabolized in the liver
- Dose adjustment needed when co-administering liver enzyme inducer drugs
- Possible reduction of maintenance dose with enzyme inhibitor drugs
Contraindications
- Hypersensitivity to any of the ingredients
- Patients receiving live virus immunization
Side Effects
- GI disturbances
- Musculoskeletal effects
- Endocrine effects
- Neuropsychiatric effects
- Ophthalmic effects
- Fluid and electrolyte disturbances
- Susceptibility to infection
- Impaired healing
- Hypersensitivity reactions
- Skin-related effects
- Myocardial rupture risk
- Thromboembolism risk
Pregnancy and Lactation
- Cautions in pregnancy due to potential risk of intrauterine growth retardation
- Excretion in breast milk
- Benefits versus risks considerations
Precautions and Warnings
- Special caution and monitoring for specific clinical conditions like cardiac disease, hypertension, ulcerative colitis, diabetes mellitus, myasthenia gravis, etc.
Use in Special Populations
- Hepatic impairment: Monitor and adjust dose carefully
- Renal impairment: No special precautions needed
- Elderly patients: Adverse effects may have more serious consequences
Therapeutic Class
- Glucocorticoids
Storage Conditions
- Cool (below 25°C) and dry place
- Protected from light and moisture
- Keep out of the reach of children