Refla 24 mg (Tablet)
Unit Price: ৳ 30.00 (2 x 10: ৳ 600.00)
Strip Price: ৳ 300.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Deflazacort |
| Company | Jenphar bangladesh ltd |
| Also available as |
Indications
- Anaphylaxis
- Asthma
- Severe hypersensitivity reactions
- Rheumatoid arthritis
- Juvenile chronic arthritis
- Polymyalgia rheumatica
- Systemic lupus erythematosus
- Dermatomyositis
- Mixed connective tissue disease
- Polyartritis nodosa
- Sarcoidosis
- Pemphigus
- Bullous pemphigoid
- Pyoderma gangrenosum
- Minimal change nephrotic syndrome
- Acute interstitial nephritis
- Rheumatic carditis
- Ulcerative colitis
- Crohn's disease
- Uveitis
- Optic neuritis
- Autoimmune haemolytic anaemia
- Idiopathic thrombocytopenic purpura
- Acute leukaemia
- Lymphatic leukaemia
- Malignant lymphoma
- Multiple myeloma
- Immune suppression in transplantation
Pharmacology
- Anti-inflammatory action
- Inhibition of Phospholipase A2 enzyme
- Prostaglandin synthesis inhibition
- Immunosuppressive action
- Decreased release of certain immune system chemicals
Dosage & Administration
- Adults dosage range: 3-120 mg/day
- Maintenance dose range for most conditions: 3-18 mg/day
- Children dosage range: 0.25-1.5 mg/kg/day
- Alternate day administration for children
- General guidance for specific conditions
Interaction
- Metabolized in the liver
- Recommended maintenance dose adjustment when co-administered with liver enzyme inducers or inhibitors
Contraindications
- Hypersensitivity to ingredients
- Patients receiving live virus immunization
Side Effects
- GI disturbances
- Musculoskeletal effects
- Endocrine effects
- Neuropsychiatric effects
- Ophthalmic effects
- Fluid and electrolyte disturbances
- Increased susceptibility to infection
- Impaired healing
- Hypersensitivity reactions
- Skin effects: atrophy, striae, telangiectasia, acne
- Myocardial rupture
- Thromboembolism
Pregnancy & Lactation
- Placental crossing
- Risk of intrauterine growth retardation
- Prescription considerations for pregnant women
- Excretion in breast milk
- Potential systemic effects on infants
- Adrenal suppression in infants of mothers taking higher doses
Precautions & Warnings
- Special caution for specific clinical conditions
- Frequent patient monitoring for certain conditions
- Dietary considerations for salt and potassium
- Precautions for specific diseases and disorders
- Special caution for emotional instability or psychotic tendency, epilepsy
- Monitoring and precautions for hepatic impairment
- Monitoring and precautions for renal impairment
- Considerations for elderly patients
Use in Special Populations
- Monitoring and dose adjustment for hepatic impairment
- Special precautions for renally impaired patients
- Considerations for elderly patients
Therapeutic Class
- Glucocorticoids
Storage Conditions
- Cool and dry storage
- Protection from light and moisture
- Keep out of the reach of children