Dezacot 6 mg (Tablet)

Unit Price: ৳ 8.03 (3 x 10: ৳ 240.90)
Strip Price: ৳ 80.30

Medicine Details

Title

  • Dezacot

Categories

  • Medicine
  • Pharmaceutical

Description

  • Dezacot is a glucocorticoid indicated for various conditions such as anaphylaxis, asthma, rheumatoid arthritis, lupus erythematosus, nephrotic syndrome, and others. It provides anti-inflammatory and immunosuppressive actions.

Indications

  • Anaphylaxis
  • Asthma
  • Severe hypersensitivity reactions
  • Rheumatoid arthritis
  • Juvenile chronic arthritis
  • Polymyalgia rheumatica
  • Systemic lupus erythematosus
  • Dermatomyositis
  • Mixed connective tissue disease
  • Polyartritis nodosa
  • Sarcoidosis
  • Pemphigus
  • Bullous pemphigoid
  • Pyoderma gangrenosum
  • Minimal change nephrotic syndrome
  • Acute interstitial nephritis
  • Rheumatic carditis
  • Ulcerative colitis
  • Crohn's disease
  • Uveitis
  • Optic neuritis
  • Autoimmune haemolytic anaemia
  • Idiopathic thrombocytopenic purpura
  • Acute lymphatic leukaemia
  • Malignant lymphoma
  • Multiple myeloma
  • Immune suppression in transplantation

Pharmacology

  • Inhibits Phospholipase A2 enzyme
  • Decreases release of immune system chemicals

Dosage & Administration

  • Adult dosage range: 3-120 mg/day
  • Children dosage range: 0.25-1.5 mg/kg/day
  • Deflazacort withdrawal protocol

Interaction

  • Metabolized in the liver
  • Recommendation to adjust maintenance dose with liver enzyme inducers or inhibitors

Contraindications

  • Hypersensitivity to ingredients
  • Patients receiving live virus immunization

Side Effects

  • GI disturbances
  • Musculoskeletal effects
  • Endocrine effects
  • Neuropsychiatric effects
  • Ophthalmic effects
  • Fluid and electrolyte disturbances
  • Increased susceptibility to infection
  • Impaired healing
  • Hypersensitivity reactions
  • Skin atrophy
  • Striae
  • Telangiectasia
  • Acne
  • Myocardial rupture risk
  • Thromboembolism risk

Pregnancy & Lactation

  • Potential risk of intrauterine growth retardation
  • Excretion in breast milk
  • Infant adrenal suppression risk

Precautions & Warnings

  • Caution in cardiac disease or congestive heart failure
  • Salt and water retention risk
  • Caution in gastritis, oesophagitis, diverticulitis, ulcerative colitis
  • Diabetes mellitus
  • Osteoporosis risk
  • Myasthenia gravis
  • Renal insufficiency
  • Emotional instability
  • Psychotic tendency
  • Epilepsy
  • Corticosteroid-induced myopathy risk
  • Liver failure
  • Ocular herpes simplex caution

Use in Special Populations

  • Hepatic impairment considerations
  • Renal impairment considerations
  • Elderly considerations

Therapeutic Class

  • Glucocorticoids

Storage Conditions

  • Store below 25°C
  • Protect from light and moisture
  • Keep out of reach of children

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