Xelopes 40 mg (Capsule (Enteric Coated))
Unit Price: ৳ 7.02 (5 x 6: ৳ 210.60)
Strip Price: ৳ 42.12
Medicine Details
Category | Details |
---|---|
Generic | Omeprazole |
Company | Beacon pharmaceuticals plc |
Also available as |
Indications
- Treatment of gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer treatment
- Prophylaxis for patients with a history of NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease treatment
- Long-term management of acid reflux disease
- Treatment of acid-related dyspepsia
- Severe ulcerating reflux esophagitis treatment
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome treatment
- Helicobacter pylori-induced peptic ulcer treatment
Pharmacology
- Inhibitor of gastric acid secretion
- Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
- Onset of antisecretory effect within one hour
- Maximum effect occurring within two hours
- Inhibition of secretion lasts up to 72 hours
- Gradual return of secretory activity over 3 to 5 days after discontinuation
Dosage
- Oral and IV dosage instructions for different indications and conditions
Administration
- Directions for use of IV Injection
- Directions for use of IV Infusion
Interaction
- Potential interactions with other medications metabolized by cytochrome P450
- Monitoring and dose adjustment recommendations for concurrent use with warfarin or phenytoin
- Increased plasma concentrations during concomitant administration with clarithromycin
Contraindications
- Known hypersensitivity to omeprazole
Side Effects
- Mild and reversible adverse reactions
- Skin rash, urticaria, and pruritus reported
- Photosensitivity, bullous eruption, erythema multiforme, angioedema, and alopecia reported
- Diarrhoea, headache, constipation, nausea/vomiting, flatulence, and abdominal pain reported
- Dry mouth, stomatitis, and candidiasis reported
- Paraesthesia, dizziness, light headedness, and feeling faint associated with treatment
- Somnolence, insomnia, and vertigo reported
- Reversible mental confusion, agitation, depression, and hallucinations reported
- Arthritic and myalgic symptoms reported
Pregnancy & Lactation
- Results from epidemiological studies indicate no adverse effects on pregnancy or the fetus/newborn child
- Consideration for use during pregnancy
- No information available on passage into breast milk or effects on the neonate
- Discontinuation of breastfeeding if essential use is considered
Precautions & Warnings
- Avoid concomitant use of clopidogrel
- Association with increased risk for osteoporosis-related fractures
- Atrophic gastritis noted occasionally in long-term treatment
- Potential for methotrexate toxicities with concomitant use of PPIs
Therapeutic Class
- Proton Pump Inhibitor
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
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