Dexzole 60 mg (Capsule (Enteric Coated))

Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00

Medicine Details

Category Details
Generic Dexlansoprazole
Company Edruc limited
Also available as
Dexzole 30 mg capsule

Title

  • Dexzole

Category

  • Medicine
  • Pharmaceutical

Function

  • Healing of Erosive Esophagitis
  • Maintenance of Healed Erosive Esophagitis
  • Symptomatic Non-Erosive Gastroesophageal Reflux Disease

Dosage Recommendations

  • 30 mg Once daily for Maintenance of Healed erosive esophagitis and relief of heartburn
  • 30 mg Once daily for Symptomatic Non-Erosive GERD
  • 60 mg Once daily for Healing of erosive esophagitis
  • One 30 mg tablet once daily for 6 months for Maintenance of healed erosive esophagitis and relief of heartburn
  • One 30 mg tablet once daily for Symptomatic Non-Erosive GERD

Administration

  • Can be taken without regard to food
  • Should be swallowed whole
  • Alternatively, capsules can be administered by opening the capsule and swallowing the intact granules on one tablespoon

Mode of Action

  • Proton Pump Inhibitor (PPI)
  • Suppresses gastric acid secretion by specific inhibition of the (H+/K+)-ATPase in the gastric parietal cell
  • Blocks the final step of acid production
  • Supplied as a Dual Delayed Release (DDR) formulation in a capsule for oral administration

Interaction

  • With Medicine: Atazanavir, Warfarin, Tacrolimus, Clopidogrel & Methotrexate

Contraindications

  • Contraindicated in patients with known hypersensitivity to any component of the formulation

Side Effects

  • Diarrhea
  • Abdominal pain
  • Nausea
  • Vomiting
  • Flatulence

Precautions & Warnings

  • Gastric Malignancy
  • Clostridium difficile Associated Diarrhea
  • Bone fracture
  • Hypomagnesemia
  • Concomitant use with Methotrexate

Pregnancy & Lactation

  • Pregnancy Category B
  • No adequate and well-controlled studies with Dexlansoprazole in pregnant women
  • No adequate and well-controlled studies with Dexlansoprazole in lactating mother

Use in Special Populations

  • Safety and effectiveness in patients below 12 years of age have not been established
  • No dose adjustment is necessary for elderly patients
  • No dose adjustment of Dexzole is necessary for patients with renal impairment
  • No dose adjustment for patients with mild hepatic impairment
  • Consider a maximum daily dose of Dexzole 30 mg for patients with moderate hepatic impairment

Overdose Effects

  • No reports of significant overdose of Dexzole
  • Multiple doses of Dexzole 120 mg and a single dose of Dexzole 300 mg did not result in severe adverse events

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Store below 30°C temperature & in a dry place, protected from light
  • Keep all medicines out of reach of children

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