Lantidex 30 mg (Capsule (Enteric Coated))

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Indications

  • Healing of Erosive Esophagitis
  • Maintenance of Healed Erosive Esophagitis
  • Symptomatic Non-Erosive Gastroesophageal Reflux Disease

Dosage

  • 30 mg Once daily for Maintenance of Healed erosive esophagitis
  • 30 mg Once daily for Symptomatic Non-Erosive GERD
  • 60 mg Once daily for Healing of erosive esophagitis

Administration

  • Can be taken without regard to food
  • Can be administered by opening capsule and swallowing intact granules
  • Should be swallowed whole
  • Granules should not be chewed

Interaction

  • With Atazanavir, Warfarin, Tacrolimus, Clopidogrel & Methotrexate

Contraindications

  • Known hypersensitivity to any component of the formulation

Side Effects

  • Diarrhea
  • Abdominal pain
  • Nausea
  • Vomiting
  • Flatulence

Pregnancy & Lactation

  • Pregnancy Category B
  • No adequate and well-controlled studies in pregnant women or lactating mothers

Precautions & Warnings

  • Gastric Malignancy
  • Clostridium difficile Associated Diarrhea
  • Bone fracture
  • Hypomagnesemia
  • Concomitant use with Methotrexate

Use in Special Populations

  • Safety and effectiveness not established for patients below 12 years age
  • No dose adjustment is necessary for elderly patients
  • No dose adjustment for renal impairment
  • No dose adjustment for mild hepatic impairment
  • Consider maximum daily dose for moderate hepatic impairment

Overdose Effects

  • No reports of significant overdose
  • Multiple doses up to 120 mg and a single dose of 300 mg did not result in severe adverse events or death

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Store below 30°C temperature
  • Store in a dry place protected from light
  • Keep all medicines out of reach of children

Pharmacology

  • Proton Pump Inhibitor (PPI)
  • Suppresses gastric acid secretion by specific inhibition of (H+/K+)-ATPase in gastric parietal cell
  • Blocks the final step of acid production
  • Dual Delayed Release (DDR) formulation in a capsule for oral administration
  • Plasma concentration-time profile with distinct peaks
  • Extensively metabolized in the liver and excreated by urine

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