Asector 40 mg (Capsule (Enteric Coated))
Unit Price: ৳ 9.03 (7 x 4: ৳ 252.87)
Strip Price: ৳ 36.12
Medicine Details
Category | Details |
---|---|
Generic | Esomeprazole |
Company | Novo healthcare and pharma ltd |
Also available as |
Title and Categories
- Asector 40 mg Capsule
- Proton Pump Inhibitor
- Lifestyle Medicine
- Digestive Health
- Gastrointestinal Relief
Indications
- Relief from chronic heartburn symptoms
- Healing of erosive esophagitis
- Maintenance of healing of erosive esophagitis
- Eradication of Helicobacter pylori infection
- Treatment for Zollinger-Ellison Syndrome
- Management of Acid-related Dyspepsia
- Healing of Duodenal & Gastric Ulcers
Dosage Forms
- Oral tablet
- Oral capsule
- Oral suspension
- IV injection
- IV infusion
Dosage Instructions
- 20 mg or 40 mg Once Daily for 4-8 Weeks (Erosive Esophagitis)
- 20 mg Once Daily (Maintenance of Healing of Erosive Esophagitis)
- 20 mg Once Daily for 4 Weeks (Symptomatic GERD)
- Triple Therapy for Helicobacter Pylori eradication
- 20-80 mg once daily (Zollinger-Ellison Syndrome)
- 20-40 mg once daily for 2-4 weeks (Acid-related Dyspepsia)
- 20 mg once daily for 2-4 weeks (Duodenal Ulcer)
- 20-40 mg once daily for 4-8 weeks (Gastric Ulcer)
Administration Instructions
- Swallow tablet or capsule whole, one hour before a meal
- Prepare oral suspension by mixing with water
- Administer IV injection or infusion as per specified duration
Pharmacology
- Mechanism of Action: Inhibition of H+/K+-ATPase
- Absorption: Peak plasma levels at approximately 1.5 hours
- Distribution: 97% bound to plasma proteins
- Metabolism: Extensively metabolized by CYP enzymes
- Excretion: Plasma elimination half-life of approximately 1–1.5 hours
Interactions
- CYP Metabolism:
- Metabolized by CYP2C19 and CYP3A4
- No clinically relevant interactions with specific CYP enzymes
- Potential Interference:
- Interference with absorption of drugs affected by gastric pH
- Specific Drug Interactions:
- Potential interaction with diazepam, ketoconazole, iron salts, and digoxin
Contraindications
- Known hypersensitivity to any of the formulation
Side Effects
- Headache
- Diarrhoea
- Nausea
- Flatulence
- Abdominal pain
- Constipation
- Dry mouth
Use in Special Populations
- Paediatric Use: Safety and effectiveness not established
- Geriatric Use: No overall differences in safety and efficacy observed
- Hepatic Insufficiency: No dosage adjustment recommended for mild to moderate insufficiency
- Renal Insufficiency: Pharmacokinetics not expected to be altered
Overdose Effects
- Acute toxicity signs: reduced motor activity, changes in respiratory frequency, tremor, convulsions
- No specific antidote known
- Symptomatic and supportive treatment recommended
Storage Conditions
Store at temperature not exceeding 30°C, protect from light and moisture
Chemical Structure
- Molecular Formula: C17H19N3O3S
- Chemical Structure Image: https://medex.com.bd/storage/res/g-res-433-esomeprazole-chemical-structure-Tj2Jfp1VmPkRjNXznKqC.svg
Commonly Asked Questions
- Uses:
- Treats gastroesophageal reflux disease (GERD), ulcers, and other conditions involving excess stomach acid
- Side Effects: Includes headaches, diarrhea, nausea, and other common symptoms
- Pregnancy & Breastfeeding: No specific side effects reported, discuss with doctor if essential
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