Flamitrol 0.1% (Ophthalmic Solution)

5 ml drop: ৳ 100.30

Medicine Details

Indications

  • Allergic non-infectious blepharitis and conjunctivitis
  • Non-infectious keratitis
  • Punctate keratitis
  • Disciform keratitis
  • Inflammation of the anterior uvea (iritis, iridocyclitis)
  • Scleritis
  • Episcleritis
  • Myositis
  • Post-operative management of cataract
  • Strabismus
  • Other ocular surgeries

Pharmacology

  • Dexamethasone is a cortisone derivative
  • High activity due to the presence of methyl group in the 16-alpha position
  • Therapeutic concentrations of Dexamethasone are found in both the cornea and aqueous humor
  • Concentrations persist for 4-6 hours
  • Inhibits the phospholipase A2
  • Inhibits the chemotactic infiltration of neutrophils into the site of inflammation

Dosage & Administration

  • Instill 1 drop into the conjunctival sac 3-5 times per day
  • Acute cases: up to 1 drop every hour if necessary
  • Apply a small amount into the conjunctival sac 3-4 times per day
  • Slowly close your eyes without blinking
  • Keep your eyes closed for 1 to 2 minutes
  • Minimize the dose when desired improvement is observed

Interaction

  • Specific drug interaction studies have not been conducted with Flamitrol

Contraindications

  • Injuries and ulcerating processes of the cornea
  • Purulent infections of the conjunctiva and eyelids
  • Tuberculosis
  • Mycosis
  • Glaucoma

Side Effects

  • Reversible rise in intraocular pressure in predisposed patients after several weeks of corticosteroid application

Pregnancy & Lactation

  • Adverse effect on the fetus based on animal experiments
  • Dexamethasone ophthalmic preparation should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus

Precautions & Warnings

  • Corticosteroids may mask, activate, or aggravate an infection of the eye
  • Do not touch dropper tip to any surface

Overdose Effects

  • Overdose through local or accidental oral administration is not likely

Storage Conditions

  • Store at room temperature
  • Protect from light
  • Contents should not be used more than one month after first opening of the bottle

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