Stedex 0.1% (Ophthalmic Solution)
Medicine Details
| Category | Details |
|---|---|
| Generic | Dexamethasone ophthalmic |
| Company | Navana pharmaceuticals ltd |
Indications
- Treatment of allergic non-infectious blepharitis and conjunctivitis
- Treatment of non-infectious keratitis, punctate keratitis, disciform keratitis
- Treatment of inflammation of the anterior uvea (iritis, iridocyclitis)
- Treatment of scleritis, episcleritis and myositis
- Post-operative management of cataract, strabismus & other ocular surgeries
Pharmacology
High activity due to the presence of methyl group in the 16-alpha position and of a fluorine atom in the 9-alpha position. Anti-inflammatory activity is 30 times greater than hydrocortisone. Also anti-allergic, anti-exudative and anti-proliferative. Inhibits phospholipase A2, the first step in prostaglandin synthesis. Inhibits the chemotactic infiltration of neutrophils into the site of inflammation.
Dosage & Administration
- Instill 1 drop into the conjunctival sac 3-5 times per day for ophthalmic solution
- Apply a small amount into the conjunctival sac 3-4 times per day for ophthalmic ointment
Interaction
Specific drug interaction studies have not been conducted with Stedex.
Contraindications
- Injuries and ulcerating processes of the cornea, particularly those of bacterial or viral origin
- Purulent infections of the conjunctiva and eyelids
- Tuberculosis, mycosis, glaucoma
Side Effects
Reversible rise in intraocular pressure in predisposed patients
Pregnancy & Lactation
Use during pregnancy only if the potential benefit justifies the potential risk to the fetus
Precautions & Warnings
- Corticosteroids may mask, activate or aggravate an infection of the eye
- If no improvement is seen after a few days application, other form of treatment should be used
- Do not touch dropper tip to any surface
Overdose Effects
Overdose through local or accidental oral administration is not likely
Storage Conditions
Store at room temperature & protect from light. Use contents within one month after first opening of the bottle