Ema 40 mg/vial (IV Injection)
40 mg vial: ৳ 85.00
Medicine Details
Category | Details |
---|---|
Generic | Esomeprazole |
Company | Globe pharmaceuticals ltd |
Also available as |
Indications
- Relief from chronic heartburn symptoms
- Healing of erosive esophagitis
- Maintenance of healing of erosive esophagitis
- Eradication of Helicobacter pylori infection
- Zollinger-Ellison Syndrome
- Acid-related Dyspepsia
- Duodenal and Gastric ulcer
Pharmacology
- Proton pump inhibitor
- Suppression of gastric acid secretion
- Specific inhibition of the H+/K+-ATPase
- First single optical isomer of proton pump inhibitor
- Enteric-coated pellet formulation
- Metabolized in the liver by cytochrome P450 (CYP) enzyme system
- Plasma protein binding
- Plasma elimination half-life
- Combination therapy with antimicrobials
Dosage
- Oral dosage form
- IV Injection or IV infusion
- Specific dosage for different indications
- Dosage for pediatric patients
- Dosage for risk reduction of rebleeding of Gastric or Duodenal Ulcers following therapeutic endoscopy
Administration
- Swallowed whole and taken one hour before a meal
- Oral suspension administration
- IV Injection administration
Interaction
- Extensively metabolized in the liver by CYP2C19 and CYP3A4
- Inhibition of CYP2C19
- Potential interference with drug absorption
- No clinically significant interactions with specific drugs
Contraindications
- Known hypersensitivity to any of the formulation
Side Effects
- Headache
- Diarrhoea
- Nausea
- Flatulence
- Abdominal pain
- Constipation
- Dry mouth
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- No teratogenic effects in animal studies
- Excretion of esomeprazole in milk not studied
- Discontinuation of breastfeeding if essential
Precautions & Warnings
- Symptomatic response does not preclude the presence of gastric malignancy
- Instructions for patients with difficulty swallowing capsules
- Use of antacids while taking Ema
- Safety and effectiveness in pediatric and geriatric patients
- No dosage adjustment for mild to moderate hepatic insufficiency
- No alteration of pharmacokinetics in renal impairment
Use in Special Populations
- Safety and effectiveness not established in pediatric patients
- No overall differences in safety and efficacy in elderly patients
- No dosage adjustment for mild to moderate hepatic insufficiency
- No alteration of pharmacokinetics in renal impairment
Overdose Effects
- Signs of acute toxicity in animal studies
- No specific antidote known
- Symptomatic and supportive treatment recommended
- Exclusion of multiple drug ingestion
Storage Conditions
- Temperature not exceeding 30°C
- Dry place
- Protection from light and moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C17H19N3O3S
- Chemical Structure Image
Common Questions about Ema 40 mg/vial Injection
- Use as a proton pump inhibitor
- Treatment of gastroesophageal reflux disease (GERD)
- Multiple uses including heartburn relief and ulcer treatment
- Common side effects
- Safety considerations for pregnant or breastfeeding individuals
- Onset of action
- Quick Tips for usage
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