Nefrofer 100 mg/5 ml (IV Injection or Infusion)
5 ml ampoule: ৳ 350.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Iron sucrose |
| Company | Chemist laboratories ltd |
Indications
- Treats Nefrofer deficiency
- Rapid Nefrofer supply
- Inflammatory bowel disease treatment
- Chronic kidney disease treatment
- Anemia treatment
Pharmacology
- Therapeutic class: haematinic
- Brown, sterile, aqueous complex of Polynuclear Iron (III) Hydroxide in Sucrose
- Contains approximately 30% Sucrose w/v
- pH of 10.5-11.1
- Dissociates into Iron and Sucrose
- Iron transfers to liver and bone marrow
- Iron binds to plasma transferrin
- Elimination half-life of 6 hours
Dosage
- Adult dosage: 5-10 ml Iron Sucrose Injection
- Children dosage: Limited data available
- Frequency: once to three times a week
- Dependent on hemoglobin level
Administration
- Intravenous injection
- Maximum 10 ml Iron Sucrose Injection per injection
- Test dose before administration
- Slow intravenous injection recommended
- Infusion with 0.9% w/v Sodium Chloride solution
Interaction
- Not studied for drug interactions
- Not to be administered concomitantly with oral iron preparations
Contraindications
- Iron overload
- Known hypersensitivity to Iron Sucrose
- Anemia not caused by Iron deficiency
- History of allergic disorders, liver disease, infections
Side Effects
- Hypotension
- Nausea
- Headache
- Vomiting
- Diarrhea
- Fever
- Abdominal pain
- Dizziness
- Pruritus
- Hypersensitivity reactions
Pregnancy & Lactation
- Pregnancy Category-B
- Caution advised during lactation
Precautions & Warnings
- Monitoring of hematologic and haematinic parameters
- Caution for hypersensitivity reactions
- Monitoring of hypotension
Use in Special Populations
- Safety and effectiveness not established for pediatric use
- No overall differences in safety observed for geriatric use
Overdose Effects
- May lead to accumulation of Iron in storage sites
- Monitoring of Iron parameters recommended
- Symptoms include hypotension, headache, vomiting, nausea, dizziness
Therapeutic Class
- Parenteral Iron Preparations
Storage Conditions
- Store in a cool and dry place
- Protected from light
- Do not freeze
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