ETP 25 mg (Tablet)

Unit Price: ৳ 511.33 (1 x 7: ৳ 3,579.31)
Strip Price: ৳ 3,579.31

Medicine Details

Category Details
Generic Eltrombopag olamine
Company Beacon pharmaceuticals plc
Also available as

Indications

  • Treatment of thrombocytopenia in patients with persistent or chronic immune thrombocytopenia
  • Treatment of thrombocytopenia in patients with hepatitis C infection
  • Treatment of severe aplastic anemia

Pharmacology

Eltrombopag Olamine is a small molecule thrombopoietin (TPO) receptor agonist.

Dosage & Administration

  • Route of administration: Oral route
  • Recommended dosage for various conditions:
    • Persistent or chronic immune thrombocytopenia
    • Adult and pediatric patients with ITP
    • Pediatric patients with ITP aged 1 to 5 years
    • Chronic hepatitis C associated thrombocytopenia
    • First line severe aplastic anemia
    • Refractory severe aplastic anemia

Interaction

  • Drug interaction with medication: Take eltrombopag at least 2 hours before or 4 hours after medications or products containing polyvalent cations
  • Drug interaction with food and others: Take eltrombopag at least 2 hours before or 4 hours after consuming calcium rich foods

Contraindications

Eltrombopag is contraindicated in patients with known hypersensitivity to eltrombopag or any components of this product.

Side Effects

  • Anemia
  • Nausea
  • Pyrexia
  • ALT increased
  • Cough
  • Fatigue
  • Headache
  • Diarrhea

Pregnancy & Lactation

  • No sufficient data available for assessing associated risks
  • Breastfeeding not recommended during treatment

Precautions & Warnings

  • Hepatitis C patients: Monitor liver function before and during therapy
  • Risk of myelodysplastic syndromes progression: Monitor platelet counts regularly

Use in Special Populations

  • Use in children and adolescents: Safety and efficacy in pediatric patients below the age of 1 year with ITP have not been established
  • Safety and efficacy in pediatric patients with thrombocytopenia associated with chronic hepatitis C and refractory severe aplastic anemia: Not established

Overdose Effects

In case of overdose, consider oral administration of a metal cation containing preparation to chelate eltrombopag and limit absorption

Therapeutic Class

Haemostatic drugs

Storage Conditions

Store in a cool and dry place protected from light, keep away from the reach of children

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