Epa 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 4.00 (5 x 10: ৳ 200.00)
Strip Price: ৳ 40.00

Medicine Details

Category Details
Generic Esomeprazole
Company Zenith pharmaceuticals ltd
Also available as
Epa 20 mg capsule

Title

Epa 20 mg Tablet

Categories

  • Medicine
  • Gastroenterology

Description

Epa 20 mg Tablet is a proton pump inhibitor (PPI) used to treat gastroesophageal reflux disease (GERD), ulcers, and other conditions that involve too much stomach acid.

Color options

  • White

Dimensions

Standard tablet size

Functions

  • Relieves symptoms of GERD
  • Heals erosive esophagitis
  • Aids in maintenance of healing of erosive esophagitis
  • Eradicates Helicobacter pylori infection
  • Treats Zollinger-Ellison Syndrome
  • Relieves symptoms of acid-related dyspepsia
  • Heals duodenal and gastric ulcers

Materials

  • Active ingredient: Esomeprazole
  • Enteric-coated pellet formulation
  • Dry powder for IV injection

Technical specifications

  • Absorption:
    • Peak plasma levels: Approximately 1.5 hours
    • Systemic bioavailability: Approximately 90% after repeated once daily dosing
  • Distribution:
    • Plasma protein binding: 97%
    • Apparent volume of distribution at steady state: Approximately 16 L
  • Metabolism:
    • Dependent on:
      • CYP2C19 isoenzyme
      • CYP3A4
  • Excretion:
    • Plasma elimination half-life: Approximately 1–1.5 hours
    • Excretion of parent drug in urine: <1%

Design elements

  • Tablet
  • Capsule
  • Oral suspension
  • IV Injection

Usability features

  • Tablet or capsule: Swallowed whole and taken one hour before a meal
  • Oral Suspension: Mixed with water and swallowed within 30 minutes
  • IV Injection: Requires 0.9% Sodium Chloride for reconstitution

Interaction

  • Metabolism by liver enzymes:
    • CYP2C19
    • CYP3A4
  • Potential interference with absorption of certain drugs:
    • Ketoconazole
    • Iron salts
    • Digoxin

Contraindications

  • Known hypersensitivity to any of the formulation

Side effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy and lactation

  • Pregnancy: No adequate and well-controlled studies
  • Lactation: Excretion in milk not studied; breastfeeding should be discontinued if essential

Precautions and warnings

  • Symptomatic response to therapy does not preclude the presence of gastric malignancy
  • Special instructions for patients with difficulty swallowing capsules

Special populations

  • Pediatric Use: Safety and effectiveness not established
  • Geriatric Use: No overall differences in safety and efficacy observed
  • Hepatic Insufficiency: No dosage adjustment recommended for mild to moderate insufficiency
  • Renal Insufficiency: Pharmacokinetics not expected to be altered

Overdose effects

Acute toxicity in rats with dosage 103 times the human equivalent; no specific antidote known

Storage conditions

Store at a temperature not exceeding 30°C, protect from light and moisture

Compound summary

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure: Image available

Commonly asked questions

  • What is Epa 20 mg Tablet?: A proton pump inhibitor for reducing stomach acid production
  • What is Epa 20 mg Tablet used for?: Treats GERD, heals erosive esophagitis, prevents recurrence, and more
  • What are the side effects of Epa 20 mg Tablet?: Common side effects include headaches, diarrhea, nausea, and more
  • Can I take Epa 20 mg Tablet if I am pregnant or breastfeeding?: Discuss with a doctor about risks and benefits
  • How long does it take for Epa 20 mg Tablet to work?: Usually starts working within a few hours

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