Epa 20 mg (Tablet (Enteric Coated))
Unit Price: ৳ 4.00 (5 x 10: ৳ 200.00)
Strip Price: ৳ 40.00
Medicine Details
Category | Details |
---|---|
Generic | Esomeprazole |
Company | Zenith pharmaceuticals ltd |
Also available as |
Title
Epa 20 mg Tablet
Categories
- Medicine
- Gastroenterology
Description
Epa 20 mg Tablet is a proton pump inhibitor (PPI) used to treat gastroesophageal reflux disease (GERD), ulcers, and other conditions that involve too much stomach acid.
Color options
- White
Dimensions
Standard tablet size
Functions
- Relieves symptoms of GERD
- Heals erosive esophagitis
- Aids in maintenance of healing of erosive esophagitis
- Eradicates Helicobacter pylori infection
- Treats Zollinger-Ellison Syndrome
- Relieves symptoms of acid-related dyspepsia
- Heals duodenal and gastric ulcers
Materials
- Active ingredient: Esomeprazole
- Enteric-coated pellet formulation
- Dry powder for IV injection
Technical specifications
- Absorption:
- Peak plasma levels: Approximately 1.5 hours
- Systemic bioavailability: Approximately 90% after repeated once daily dosing
- Distribution:
- Plasma protein binding: 97%
- Apparent volume of distribution at steady state: Approximately 16 L
- Metabolism:
- Dependent on:
- CYP2C19 isoenzyme
- CYP3A4
- Dependent on:
- Excretion:
- Plasma elimination half-life: Approximately 1–1.5 hours
- Excretion of parent drug in urine: <1%
Design elements
- Tablet
- Capsule
- Oral suspension
- IV Injection
Usability features
- Tablet or capsule: Swallowed whole and taken one hour before a meal
- Oral Suspension: Mixed with water and swallowed within 30 minutes
- IV Injection: Requires 0.9% Sodium Chloride for reconstitution
Interaction
- Metabolism by liver enzymes:
- CYP2C19
- CYP3A4
- Potential interference with absorption of certain drugs:
- Ketoconazole
- Iron salts
- Digoxin
Contraindications
- Known hypersensitivity to any of the formulation
Side effects
- Headache
- Diarrhea
- Nausea
- Flatulence
- Abdominal pain
- Constipation
- Dry mouth
Pregnancy and lactation
- Pregnancy: No adequate and well-controlled studies
- Lactation: Excretion in milk not studied; breastfeeding should be discontinued if essential
Precautions and warnings
- Symptomatic response to therapy does not preclude the presence of gastric malignancy
- Special instructions for patients with difficulty swallowing capsules
Special populations
- Pediatric Use: Safety and effectiveness not established
- Geriatric Use: No overall differences in safety and efficacy observed
- Hepatic Insufficiency: No dosage adjustment recommended for mild to moderate insufficiency
- Renal Insufficiency: Pharmacokinetics not expected to be altered
Overdose effects
Acute toxicity in rats with dosage 103 times the human equivalent; no specific antidote known
Storage conditions
Store at a temperature not exceeding 30°C, protect from light and moisture
Compound summary
- Molecular Formula: C17H19N3O3S
- Chemical Structure: Image available
Commonly asked questions
- What is Epa 20 mg Tablet?: A proton pump inhibitor for reducing stomach acid production
- What is Epa 20 mg Tablet used for?: Treats GERD, heals erosive esophagitis, prevents recurrence, and more
- What are the side effects of Epa 20 mg Tablet?: Common side effects include headaches, diarrhea, nausea, and more
- Can I take Epa 20 mg Tablet if I am pregnant or breastfeeding?: Discuss with a doctor about risks and benefits
- How long does it take for Epa 20 mg Tablet to work?: Usually starts working within a few hours
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