Alexa 4000 Anti-Xa IU/0.4 ml (SC Injection)

0.4 ml pre-filled syringe: ৳ 450.00

Medicine Details

Category Details
Generic Enoxaparin sodium
Company Healthcare pharmaceuticals ltd
Also available as
Alexa 6000 anti xa injection Alexa 8000 anti xa injection

Indications

  • Treatment of deep vein thrombosis, with or without pulmonary embolism
  • Treatment of unstable angina and non-Q-wave myocardial infarction
  • Prevention of thrombus formation in extra corporeal circulation during haemodialysis
  • Prophylaxis of venous thromboembolic disease in surgical and medical patients

Composition

  • Enoxaparin Sodium BP 20 mg pre-filled syringe
  • Enoxaparin Sodium BP 40 mg pre-filled syringe
  • Enoxaparin Sodium BP 60 mg pre-filled syringe
  • Enoxaparin Sodium BP 80 mg pre-filled syringe

Pharmacology

  • Low molecular weight heparin with high anti-Xa activity
  • Low anti-lla or antithrombin activity
  • Metabolized primarily in the liver

Dosage

  • Subcutaneous dosage for different indications and patient types

Administration

  • Instructions for self-injecting with pre-filled syringes
  • Preparation of injection site
  • Selecting and adjusting dosage
  • Injecting technique
  • Disposal of used syringe

Interaction

  • Recommendation to discontinue agents affecting hemostasis prior to therapy
  • List of medications to be discontinued or used with careful monitoring

Contraindications

  • Known hypersensitivity to Enoxaparin Sodium or heparin
  • Active major bleeding
  • High risk of uncontrolled hemorrhage

Side Effects

  • Haemorrhage
  • Thrombocytopenia
  • Elevations of serum aminotransferase
  • Pain and skin reactions at injection sites

Pregnancy & Lactation

  • Category B pregnancy
  • Use only if clearly needed during pregnancy
  • Unknown excretion in human milk

Precautions & Warnings

  • Deep subcutaneous administration
  • Caution in conditions with increased potential for bleeding
  • Recommendation for platelet count measurement

Use in Special Populations

  • Dose in elderly patients
  • Dose in renal impairment
  • Dose in hepatic impairment

Overdose Effects

  • Hemorrhagic complications
  • Neutralization with protamine sulfate

Therapeutic Class

  • Parenteral anti-coagulants

Storage Conditions

  • Cool and dry storage
  • Protection from light and moisture
  • Do not store above 25°C
  • Keep out of the reach of children

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