Alexa 8000 Anti-Xa IU/0.8 ml (SC Injection)

0.8 ml pre-filled syringe: ৳ 750.00

Medicine Details

Category Details
Generic Enoxaparin sodium
Company Healthcare pharmaceuticals ltd
Also available as
Alexa 4000 anti xa injection Alexa 6000 anti xa injection

Indications

  • Treatment of deep vein thrombosis, with or without pulmonary embolism
  • Treatment of unstable angina and non-Q-wave myocardial infarction, administered concurrently with aspirin
  • Prevention of thrombus formation in the extra-corporal circulation during haemodialysis
  • Prophylaxis of venous thromboembolic disease in medical patients bedridden due to acute illness
  • Prophylaxis of venous thromboembolic disease in surgical patients

Composition

  • 0.2 ml pre-filled syringe contains Enoxaparin Sodium BP 20 mg equivalent to 2000 anti-Xa III
  • 0.4 ml pre-filled syringe contains Enoxaparin Sodium BP 40 mg equivalent to 4000 anti-Xa III
  • 0.6 ml pre-filled syringe contains Enoxaparin Sodium BP 60 mg equivalent to 6000 anti-Xa IU
  • 0.8 ml pre-filled syringe contains Enoxaparin Sodium BP 80 mg equivalent to 8000 anti-Xa IU

Pharmacology

Low molecular weight heparin with high anti-Xa activity and low anti-lla or antithrombin activity. Metabolized in the liver.

Dosage

Varies for different indications, administered subcutaneously or orally

Administration

Subcutaneous injection, detailed instructions provided for self injection

Interaction

Agents affecting hemostasis should be discontinued prior to Alexa therapy

Contraindications

Known hypersensitivity, active major bleeding, high risk of uncontrolled hemorrhage

Side Effects

  • Haemorrhage (bleeding)
  • Thrombocytopenia
  • Elevations of serum aminotransferase
  • Pain, bluish marks at injection sites
  • Skin rash at injection sites
  • Neuraxial hematomas with concurrent use of Alexa and spinal/epidural anesthesia resulting in neurologic injuries

Pregnancy & Lactation

Category B. No evidence of crossing the placental barrier. Use during pregnancy only if clearly needed. Potential excretion in human milk.

Precautions & Warnings

Should be used with caution in conditions with increased potential for bleeding. Regular platelet count monitoring recommended.

Use in Special Populations

  • Elderly Patients: No dosage adjustment necessary
  • Renal Impairment: Caution for moderate and mild impairment, dosage adjustments for severe impairment
  • Hepatic Impairment: Caution recommended

Overdose Effects

May lead to hemorrhagic complications. Protamine sulfate can be used for neutralization.

Therapeutic Class

Parenteral anti-coagulants

Storage Conditions

Store in a cool and dry place, protect from light and moisture, below 25°C, keep out of reach of children

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