Esmax 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 9.00 (5 x 4: ৳ 180.00)
Strip Price: ৳ 36.00

Medicine Details

Category Details
Generic Esomeprazole
Company Concord pharmaceuticals ltd
Also available as
Esmax 20 mg capsule

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Treatment of Zollinger-Ellison Syndrome
  • Management of acid-related Dyspepsia
  • Healing of duodenal & gastric ulcers

Pharmacology

  • Proton pump inhibitor
  • Specific inhibition of the H+/K+-ATPase
  • First single optical isomer of proton pump inhibitor
  • Better acid control than racemic proton pump inhibitors
  • Enteric-coated pellet formulation
  • Peak plasma levels occur at approximately 1.5 hours
  • Plasma protein binding is constant over the concentration range
  • Extensively metabolized in the liver
  • Plasma elimination half-life is approximately 1–1.5 hours

Dosage

  • Oral dosage form
  • IV Injection or IV infusion
  • Different dosages for different indications
  • Adult and pediatric dosage
  • Different dosages for body weights

Administration

  • Swallowed whole and taken one hour before a meal
  • Preparation of oral suspension
  • IV injection preparation and administration

Interaction

  • Metabolized by CYP2C19 and CYP3A4
  • Inhibition of CYP2C19 by medication
  • Interference with the absorption of certain drugs

Contraindications

  • Known hypersensitivity to any of the formulation

Side effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth
  • Similar adverse events during maintenance treatment

Pregnancy and lactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects in animal studies
  • Excretion in milk not studied
  • Discontinuation of breast-feeding if essential

Precautions and warnings

  • Symptomatic response does not preclude the presence of gastric malignancy
  • Guidelines for patients with difficulty swallowing capsules
  • Use of antacids while taking Esmax

Use in special populations

  • Safety and effectiveness in pediatric patients not established
  • No overall differences in safety and efficacy in the elderly
  • No dosage adjustment for mild to moderate hepatic insufficiency
  • No alteration of pharmacokinetics in renal impairment

Overdose effects

  • Lethal dose in rats
  • Signs of acute toxicity
  • No specific antidote known
  • Symptomatic and supportive treatment recommended

Storage conditions

  • Temperature not exceeding 30°C
  • Dry place
  • Protection from light and moisture
  • Keep out of reach of children

Chemical structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure Image

Commonly asked questions

  • What is Esmax 40 mg Capsule?
  • Uses of Esmax 40 mg Capsule
  • Side effects of Esmax 40 mg Capsule
  • Use in pregnancy and breastfeeding
  • Onset of action of Esmax 40 mg Capsule
  • Quick Tips for using Esmax 40 mg Capsule

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