Esmax 40 mg (Capsule (Enteric Coated))
Unit Price: ৳ 9.00 (5 x 4: ৳ 180.00)
Strip Price: ৳ 36.00
Medicine Details
Category | Details |
---|---|
Generic | Esomeprazole |
Company | Concord pharmaceuticals ltd |
Also available as |
Indications
- Relief from chronic heartburn symptoms
- Healing of erosive esophagitis
- Maintenance of healing of erosive esophagitis
- Eradication of Helicobacter pylori infection
- Treatment of Zollinger-Ellison Syndrome
- Management of acid-related Dyspepsia
- Healing of duodenal & gastric ulcers
Pharmacology
- Proton pump inhibitor
- Specific inhibition of the H+/K+-ATPase
- First single optical isomer of proton pump inhibitor
- Better acid control than racemic proton pump inhibitors
- Enteric-coated pellet formulation
- Peak plasma levels occur at approximately 1.5 hours
- Plasma protein binding is constant over the concentration range
- Extensively metabolized in the liver
- Plasma elimination half-life is approximately 1–1.5 hours
Dosage
- Oral dosage form
- IV Injection or IV infusion
- Different dosages for different indications
- Adult and pediatric dosage
- Different dosages for body weights
Administration
- Swallowed whole and taken one hour before a meal
- Preparation of oral suspension
- IV injection preparation and administration
Interaction
- Metabolized by CYP2C19 and CYP3A4
- Inhibition of CYP2C19 by medication
- Interference with the absorption of certain drugs
Contraindications
- Known hypersensitivity to any of the formulation
Side effects
- Headache
- Diarrhea
- Nausea
- Flatulence
- Abdominal pain
- Constipation
- Dry mouth
- Similar adverse events during maintenance treatment
Pregnancy and lactation
- No adequate and well-controlled studies in pregnant women
- No teratogenic effects in animal studies
- Excretion in milk not studied
- Discontinuation of breast-feeding if essential
Precautions and warnings
- Symptomatic response does not preclude the presence of gastric malignancy
- Guidelines for patients with difficulty swallowing capsules
- Use of antacids while taking Esmax
Use in special populations
- Safety and effectiveness in pediatric patients not established
- No overall differences in safety and efficacy in the elderly
- No dosage adjustment for mild to moderate hepatic insufficiency
- No alteration of pharmacokinetics in renal impairment
Overdose effects
- Lethal dose in rats
- Signs of acute toxicity
- No specific antidote known
- Symptomatic and supportive treatment recommended
Storage conditions
- Temperature not exceeding 30°C
- Dry place
- Protection from light and moisture
- Keep out of reach of children
Chemical structure
- Molecular Formula: C17H19N3O3S
- Chemical Structure Image
Commonly asked questions
- What is Esmax 40 mg Capsule?
- Uses of Esmax 40 mg Capsule
- Side effects of Esmax 40 mg Capsule
- Use in pregnancy and breastfeeding
- Onset of action of Esmax 40 mg Capsule
- Quick Tips for using Esmax 40 mg Capsule