Recogen 2000 IU (IV/SC Injection)
2000 IU pre-filled syringe: ৳ 1,000.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Erythropoietin alfa |
| Company | Aci limited |
| Also available as |
Indications
- Treatment of anemia in Chronic Kidney Disease (CKD) patients on dialysis and not on dialysis
- Treatment of anemia in Zidovudine-treated HIV-infected patients
- Treatment of anemia in patients undergoing myelosuppressive chemotherapy
- Reduction of allogeneic RBC transfusions in noncardiac, nonvascular surgery patients
- Prevention of anemia of prematurity in infants with low birth weight and premature gestational age
Description
Recombinant human erythropoietin (EPO) indicated for anemia treatment, expressed in Chinese hamster ovary cells, with a molecular weight of 30,400 daltons and identical to human urinary EPO
Dosage
- Evaluation of Iron Stores and Nutritional Factors before treatment
- Regular monitoring of hemoglobin levels for CKD patients
- Dosing adjustments based on hemoglobin rate of rise, decline, and ESA responsiveness
- Different starting doses for CKD patients on dialysis and not on dialysis, and Zidovudine-treated HIV-infected patients
- Specific dosing regimen for cancer chemotherapy patients and prevention of anemia of prematurity in infants
Administration
- Preparation and administration precautions such as not shaking the product, protecting syringe from light, and visual inspection for particulate matter and discoloration
- Discard unused portions of Erythropoietin alfa
Interaction
Potential potentiation with the therapeutic administration of a haematinic agent such as ferrous sulphate in cases of deficiency
Contraindications
- Uncontrolled hypertension
- Serious allergic reactions to Erythropoietin alfa
- Pure Red Cell Aplasia (PRCA) following treatment with any erythropoietin
Side Effects
- Adverse reactions include hypertension, arthralgia, muscle spasm, pyrexia, dizziness, medical device malfunction, vascular occlusion, and upper respiratory tract infection in CKD patients
- Adverse reactions in Zidovudine-treated HIV-infected Patients
- Adverse reactions in Cancer Patients on Chemotherapy
- Adverse reactions in Surgery Patients
- Common fall in serum ferritin values in premature infants
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Reproduction toxicology in animal studies
- Caution in nursing women, with consideration of the benefit of breast feeding to the child and the benefit of Erythropoietin alfa therapy to the woman
Overdose Effects
Wide therapeutic margin with potential for hemoglobin level elevation and severe hypertension
Therapeutic Class
Drugs for Haemolytic Hypoplastic & Renal Anemia
Storage Conditions
Store at 2ºC to 8ºC without freezing or shaking, maintaining temperature range until administration, and protecting from light