Recogen 3000 IU (IV/SC Injection)
3000 IU pre-filled syringe: ৳ 1,480.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Erythropoietin alfa |
| Company | Aci limited |
| Also available as |
Title
- Recogen Erythropoietin Alfa
Categories
- Medicine
- Erythropoiesis-Stimulating Agent
- Anemia Treatment
Description
- Recombinant human erythropoietin (EPO)
- Expressed in Chinese hamster ovary cells
- Amino acid sequence identical to human urinary EPO
- Molecular weight: 30,400 daltons
Dosage
- Evaluation of iron stores and nutritional factors
- Monitor hemoglobin levels before and during treatment
- Dosing adjustments based on hemoglobin level
- Recommended starting dose for CKD patients on dialysis and not on dialysis
- Starting dose for Zidovudine-treated HIV-infected Patients
- Starting dose for Patients on Cancer Chemotherapy
- Starting dose for Prevention of anemia of prematurity
Administration
- Do not shake before use
- Protect syringe from light
- Inspect visually for particulate matter and discoloration
- Discard unused portions
Interaction
- Potentiated effect by simultaneous administration of haematinic agent like ferrous sulphate
Contraindications
- Uncontrolled hypertension
- Serious allergic reactions to Erythropoietin alfa
- Patients who develop Pure Red Cell Aplasia (PRCA) following treatment with any erythropoietin
Side Effects
- Hypertension, arthralgia, muscle spasm, pyrexia, dizziness, medical device malfunction, vascular occlusion, upper respiratory tract infection in CKD patients
- Pyrexia, cough, rash, injection site irritation in Zidovudine-treated HIV-infected Patients
- Nausea, vomiting, myalgia, arthralgia, stomatitis, cough, weight decrease, leukopenia, bone pain, rash, hyperglycemia, and more in Cancer Patients on Chemotherapy
- Nausea, vomiting, pruritus, headache, injection site pain, chills, deep vein thrombosis, and more in Surgery Patients
- Fall in serum ferritin values in premature infants
Pregnancy & Lactation
- Caution in pregnant and nursing women
- Use only if potential benefit outweighs potential risk to the fetus
- Not recommended for pregnant or lactating surgical patients participating in an autologous blood predonation program
Overdose Effects
- Can cause hemoglobin levels above desired level
- Manage with discontinuation or reduction of dosage
- Cases of severe hypertension observed following overdose with ESAs
Therapeutic Class
- Drugs for Haemolytic Hypoplastic & Renal Anemia
Storage Conditions
- Store at 2°C to 8°C
- Do not freeze or shake