Recogen 3000 IU (IV/SC Injection)

3000 IU pre-filled syringe: ৳ 1,480.00

Medicine Details

Category Details
Generic Erythropoietin alfa
Company Aci limited
Also available as
Recogen 2000 iu injection Recogen 5000 iu injection Recogen 10000 iu injection

Title

  • Recogen Erythropoietin Alfa

Categories

  • Medicine
  • Erythropoiesis-Stimulating Agent
  • Anemia Treatment

Description

  • Recombinant human erythropoietin (EPO)
  • Expressed in Chinese hamster ovary cells
  • Amino acid sequence identical to human urinary EPO
  • Molecular weight: 30,400 daltons

Dosage

  • Evaluation of iron stores and nutritional factors
  • Monitor hemoglobin levels before and during treatment
  • Dosing adjustments based on hemoglobin level
  • Recommended starting dose for CKD patients on dialysis and not on dialysis
  • Starting dose for Zidovudine-treated HIV-infected Patients
  • Starting dose for Patients on Cancer Chemotherapy
  • Starting dose for Prevention of anemia of prematurity

Administration

  • Do not shake before use
  • Protect syringe from light
  • Inspect visually for particulate matter and discoloration
  • Discard unused portions

Interaction

  • Potentiated effect by simultaneous administration of haematinic agent like ferrous sulphate

Contraindications

  • Uncontrolled hypertension
  • Serious allergic reactions to Erythropoietin alfa
  • Patients who develop Pure Red Cell Aplasia (PRCA) following treatment with any erythropoietin

Side Effects

  • Hypertension, arthralgia, muscle spasm, pyrexia, dizziness, medical device malfunction, vascular occlusion, upper respiratory tract infection in CKD patients
  • Pyrexia, cough, rash, injection site irritation in Zidovudine-treated HIV-infected Patients
  • Nausea, vomiting, myalgia, arthralgia, stomatitis, cough, weight decrease, leukopenia, bone pain, rash, hyperglycemia, and more in Cancer Patients on Chemotherapy
  • Nausea, vomiting, pruritus, headache, injection site pain, chills, deep vein thrombosis, and more in Surgery Patients
  • Fall in serum ferritin values in premature infants

Pregnancy & Lactation

  • Caution in pregnant and nursing women
  • Use only if potential benefit outweighs potential risk to the fetus
  • Not recommended for pregnant or lactating surgical patients participating in an autologous blood predonation program

Overdose Effects

  • Can cause hemoglobin levels above desired level
  • Manage with discontinuation or reduction of dosage
  • Cases of severe hypertension observed following overdose with ESAs

Therapeutic Class

  • Drugs for Haemolytic Hypoplastic & Renal Anemia

Storage Conditions

  • Store at 2°C to 8°C
  • Do not freeze or shake

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