Recogen 5000 IU (IV/SC Injection)
5000 IU pre-filled syringe: ৳ 2,557.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Erythropoietin alfa |
| Company | Aci limited |
| Also available as |
Indications
- Treatment of anemia in Chronic Kidney Disease (CKD) patients on dialysis and not on dialysis
- Treatment of anemia in Zidovudine-treated HIV-infected patients
- Treatment of anemia in patients undergoing myelosuppressive chemotherapy
- Reduction of allogeneic RBC transfusions in patients undergoing elective surgery
- Prevention of anemia of prematurity in infants with low birth weight
Description
Recombinant human erythropoietin (EPO) expressed in Chinese hamster ovary cells, 165 amino acid sequence identical to human urinary EPO, apparent molecular weight about 30,400 daltons
Dosage
- Evaluation of Iron Stores and Nutritional Factors before treatment
- Monitoring hemoglobin levels at least weekly for CKD patients
- Dose adjustments based on hemoglobin levels and responsiveness
- Specific starting doses and dose adjustments for CKD patients on dialysis, CKD patients not on dialysis, Zidovudine-treated HIV-infected patients, cancer chemotherapy patients, and premature infants
Administration
- Preparation and Administration instructions for Erythropoietin alfa
- Guidelines for inspecting and discarding unused portions
Interaction
Potential potentiation by concurrent administration of haematinic agent such as ferrous sulphate
Contraindications
- Uncontrolled hypertension
- Serious allergic reactions to Erythropoietin alfa
- Pure Red Cell Aplasia (PRCA) following treatment with any erythropoietin
Side Effects
Adverse reactions in different patient groups, including hypertension, arthralgia, muscle spasm, pyrexia, dizziness, cough, rash, etc.
Pregnancy & Lactation
- Limited studies in pregnant women and reproduction toxicology in animals
- Caution advised in chronic renal failure patients and surgical patients participating in autologous blood predonation programme
- Caution advised in nursing women with decision to continue/discontinue breast-feeding or therapy
Overdose Effects
Wide therapeutic margin, potential hemoglobin level increase, and management with dosage reduction or phlebotomy
Therapeutic Class
Drugs for Haemolytic Hypoplastic & Renal Anemia
Storage Conditions
Store at 2°C to 8°C, avoid freezing or shaking, maintain temperature range until administration, store in original package to protect from light