Eposis 10000 IU (IV/SC Injection)
10000 IU pre-filled syringe: ৳ 4,000.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Erythropoietin alfa |
| Company | Beacon pharmaceuticals plc |
| Also available as |
Indications
- Treatment of anemia due to Chronic Kidney Disease (CKD)
- Treatment of anemia due to Zidovudine in HIV-infected patients
- Reduction of allogeneic RBC transfusions in patients undergoing elective, noncardiac, nonvascular surgery
- Prevention of anemia of prematurity in infants with a birth weight of 750 to 1500 gm and gestational age of less than 34 weeks
Description
Recombinant human erythropoietin (EPO) expressed in Chinese hamster ovary cells
Dosage
- Monitor hemoglobin levels at least weekly until stable, then at least monthly
- Evaluation of Iron Stores and Nutritional Factors required
- Dosing adjustments based on hemoglobin levels
- Different dosage recommendations for CKD patients on dialysis and not on dialysis
- Specific dosage instructions for Zidovudine-treated HIV-infected Patients and Patients on Cancer Chemotherapy
Administration
- Do not shake
- Protect syringe from light
- Visual inspection for particulate matter and discoloration prior to administration
- Disposal of unused portions
Interaction
Potentiation by simultaneous therapeutic administration of a haematinic agent
Contraindications
- Uncontrolled hypertension
- Serious allergic reactions to Erythropoietin alfa
- Patients with Pure Red Cell Aplasia (PRCA) following treatment with any erythropoietin
Side Effects
- Adverse reactions in patients with CKD, Zidovudine-treated HIV-infected Patients, Cancer Patients on Chemotherapy, Surgery Patients, and Premature infants
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Reproduction toxicology shown in animal studies
- Caution in use during pregnancy and lactation
Overdose Effects
Management with discontinuation or reduction of dosage and/or with phlebotomy
Therapeutic Class
Drugs for Haemolytic Hypoplastic & Renal Anemia
Storage Conditions
Store at 2°C to 8°C, protect from light, do not freeze or shake