Epoetin 4000 IU (IV/SC Injection)
4000 IU pre-filled syringe: ৳ 1,935.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Erythropoietin alfa |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Title
- Epoetin
Categories
- Medicine
- Healthcare
- Therapeutic Drugs
Description
- Recombinant human erythropoietin (EPO)
- Expressed in Chinese hamster ovary cells
- 165 amino acid sequence identical to human urinary EPO
- Apparent molecular weight of erythropoietin is about 30,400 daltons
Indications
- Treatment of anemia due to Chronic Kidney Disease (CKD)
- Treatment of anemia due to Zidovudine in HIV-infected patients
- Reduction of allogeneic RBC transfusions in patients undergoing elective, noncardiac, nonvascular surgery
- Prevention of anemia of prematurity in infants with low birth weight and gestational age
Dosage
- Evaluation of Iron Stores and Nutritional Factors
- Monitoring and adjusting therapy based on hemoglobin levels
- Recommended starting doses for different patient groups
- Dose adjustment guidelines for various patient scenarios
Administration
- Preparation and administration guidelines for Erythropoietin alfa
- Instructions to avoid shaking or freezing
- Visual inspection prior to administration
- Discard guidelines for unused portions
Interaction
- Potential potentiation by haematinic agents like ferrous sulphate when deficiency state exists
Contraindications
- Uncontrolled hypertension
- Serious allergic reactions to Erythropoietin alfa
- Patients who develop Pure Red Cell Aplasia (PRCA) following treatment with erythropoietin
Side effects
- Adverse reactions in different patient groups
- Specific adverse reactions reported in clinical studies for CKD, HIV-infected patients, cancer patients on chemotherapy, surgery patients, and premature infants
Pregnancy and lactation
- Use in pregnancy if potential benefit outweighs potential risk to the fetus
- Not recommended for pregnant or lactating surgical patients participating in autologous blood predonation
- Caution advised for nursing women
Overdose effects
- Management of Epoetin overdosage
- Potential effects of high hemoglobin levels
- Cases of severe hypertension observed following overdose with ESAs
Therapeutic class
- Drugs for Haemolytic Hypoplastic & Renal Anemia
Storage conditions
- Temperature storage range of 2°C to 8°C
- Avoid freezing or shaking
- Protection from light by storing in original package