Esogap 20 mg (Tablet (Enteric Coated))
Unit Price: ৳ 7.00 (10 x 10: ৳ 700.00)
Strip Price: ৳ 70.00
Medicine Details
Category | Details |
---|---|
Generic | Esomeprazole |
Company | Euro pharma ltd |
Also available as |
Indications
- Relief from chronic heartburn symptoms and other symptoms associated with GERD
- Healing of erosive esophagitis
- Maintenance of healing of erosive esophagitis
- Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease
- Zollinger-Ellison Syndrome
- Acid related Dyspepsia
- Duodenal & Gastric ulcer
Pharmacology
- Proton pump inhibitor
- Suppresses gastric acid secretion
- Specific inhibition of the H+/K+-ATPase
- First single optical isomer of proton pump inhibitor
- Better acid control than racemic proton pump inhibitors
- Peak plasma levels occur at approximately 1.5 hours
- Systemic bioavailability is approximately 90%
- 97% bound to plasma proteins
- Metabolized in the liver by the cytochrome P450 enzyme system
- Plasma elimination half-life of approximately 1–1.5 hours
Dosage
- Dosage forms: Oral, IV Injection or IV infusion
- Dose ranges for various indications
- Dose adjustment for pediatric patients
- Specific dosage for risk reduction of rebleeding of Gastric or Duodenal Ulcers
Administration
- Tablet or capsule should be swallowed whole and taken one hour before a meal
- Oral Suspension administration
- IV Injection preparation and administration
Interaction
- Metabolism by CYP2C19 and CYP3A4
- No clinically significant interactions with certain drugs
- Interference with absorption of drugs where gastric pH is important
Contraindications
- Known hypersensitivity to the formulation
Side Effects
- Headache
- Diarrhoea
- Nausea
- Flatulence
- Abdominal pain
- Constipation
- Dry mouth
Pregnancy & Lactation
- No well-controlled studies in pregnant women
- No studies on excretion in milk
- Breastfeeding discontinuation if essential
Precautions & Warnings
- Symptomatic response does not preclude the presence of gastric malignancy
- Guidance for patients with difficulty swallowing capsules
- Use of antacids
Use in Special Populations
- Safety and effectiveness for pediatric patients not established
- No overall differences in safety and efficacy in geriatric use
- No dosage adjustment for mild to moderate hepatic insufficiency
Overdose Effects
- Acute toxicity signs
- No specific antidote known
- Symptomatic and supportive treatment
- Consideration of multiple drug ingestion
Storage Conditions
- Temperature not exceeding 30°C
- Dry place, protect from light and moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C17H19N3O3S
Common Questions
- Usage as a proton pump inhibitor
- Treatment for gastroesophageal reflux disease (GERD), ulcers, and other conditions involving excess stomach acid
- Common side effects
- Pregnant or breastfeeding usage
- Duration of onset
- Quick Tips