Etoricoxib 60 mg (Tablet)

Unit Price: ৳ 6.00

Medicine Details

Category Details
Generic Etoricoxib
Company Bristol pharmaceuticals ltd
Also available as
Etoricoxib 90 mg tablet Etoricoxib 120 mg tablet

Indications

  • Symptomatic relief of Osteoarthritis (OA)
  • Symptomatic relief of Rheumatoid arthritis (RA)
  • Symptomatic relief of Ankylosing spondylitis
  • Symptomatic relief of acute gouty arthritis
  • Short-term treatment of moderate pain associated with dental surgery

Pharmacology

Potent orally active cyclooxygenase-2 (COX-2) specific inhibitor

Dosage & Administration

  • 30 mg once daily for Osteoarthritis
  • 90 mg once daily for Rheumatoid arthritis and Ankylosing spondylitis
  • 120 mg once daily for acute gouty arthritis
  • 90 mg once daily for postoperative dental surgery pain

Interaction

  • Increased prothrombin time with oral anticoagulants
  • Reduced effect of diuretics and antihypertensive drugs with NSAIDs
  • Can be used concomitantly with low-dose acetylsalicylic acid for cardiovascular prophylaxis
  • Possible increase in nephrotoxic effect of ciclosporin or tacrolimus with coadministration
  • Decreased lithium renal excretion leading to increased plasma levels of lithium

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Active peptic ulceration or gastrointestinal bleeding
  • Hypersensitivity reactions to acetylsalicylic acid or NSAIDs
  • Pregnancy and lactation
  • Severe hepatic dysfunction
  • Estimated renal creatinine clearance <30 ml/min
  • Inflammatory bowel disease
  • Congestive heart failure
  • Uncontrolled hypertension
  • Established cardiovascular disease

Side Effects

  • Palpitations
  • Fatigue
  • Influenza-like symptoms
  • Ecchymosis
  • Dry mouth
  • Taste disturbance
  • Mouth ulcer
  • Appetite and weight change
  • Atrial fibrillation
  • Transient ischaemic attack
  • Chest pain
  • Flushing
  • Cough
  • Dyspnoea
  • Epistaxis
  • Anxiety
  • Impaired mental acuity
  • Paraesthesia
  • Electrolyte disturbance
  • Myalgia
  • Arthralgia
  • Confusion
  • Hallucinations

Pregnancy & Lactation

  • Not recommended in women attempting to conceive
  • Not known whether excreted in human milk
  • Excreted in the milk of lactating rats
  • Not recommended for breastfeeding women

Precautions & Warnings

  • Caution in patients at risk of gastrointestinal complications with NSAIDs
  • Careful consideration in patients with significant cardiovascular risk factors
  • Potential impairment of renal function and renal blood flow
  • Caution in patients with cardiac failure, left ventricular dysfunction, hypertension, or edema
  • Monitoring of liver function
  • Discontinuation at signs of hypersensitivity
  • May mask fever and other signs of inflammation
  • Caution when co-administering with warfarin

Overdose Effects

No significant toxicity observed up to 500 mg single dose and 150 mg/day for 21 days

Therapeutic Class

Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

Store below 30°C, protect from light and moisture, keep out of reach of children

Chemical Structure

  • Molecular Formula: C18H15ClN2O2S
  • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-446-etoricoxib-chemical-structure-nEkDifKyFxQ9fjJEG7TQ.svg

Common Questions

  • Duration of effect
  • Onset of action
  • Pregnancy warnings
  • Habit forming tendencies
  • Breastfeeding warnings
  • Safety with alcohol
  • Impact on driving
  • Effect on kidney function
  • Effect on liver function
  • Quick Tips for usage

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