Rofin 120 mg (Tablet)

Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00

Medicine Details

Category Details
Generic Etoricoxib
Company Desh pharmaceuticals ltd
Also available as
Rofin 90 mg tablet

Indications

  • Symptomatic relief of Osteoarthritis (OA)
  • Symptomatic relief of Rheumatoid arthritis (RA)
  • Symptomatic relief of Ankylosing spondylitis
  • Symptomatic relief of acute gouty arthritis
  • Short-term treatment of moderate pain associated with dental surgery

Pharmacology

  • Orally active cyclooxygenase-2 (COX-2) specific inhibitor
  • Decreases clinical signs and symptoms with decreased potential for gastrointestinal toxicity
  • Potent and selective inhibition of COX-2
  • Decreases prostaglandin-mediated pain, inflammation, and fever

Dosage & Administration

  • Recommended doses for Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis, Acute gouty arthritis, and Postoperative dental surgery pain
  • Shortest duration possible and lowest effective daily dose should be used
  • Need for symptomatic relief and response to therapy should be re-evaluated periodically

Interaction

  • Interaction with Oral anticoagulants
  • Interaction with Diuretics, ACE inhibitors and Angiotensin II Antagonists
  • Interaction with Acetylsalicylic Acid
  • Potential interaction with Ciclosporin and tacrolimus
  • NSAIDs decrease lithium renal excretion and increase lithium plasma levels

Contraindications

  • Hypersensitivity to active substance or excipients
  • Active peptic ulceration or active gastrointestinal (GI) bleeding
  • Patients with bronchospasm, acute rhinitis, nasal polyps, angioneurotic oedema, urticaria, or allergic-type reactions after taking acetylsalicylic acid or NSAIDs including COX-2 inhibitors
  • Pregnancy and lactation
  • Severe hepatic dysfunction, Estimated renal creatinine clearance <30 ml/min
  • Children and adolescents under 16 years of age
  • Inflammatory bowel disease, Congestive heart failure, Uncontrolled hypertension, Established ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease

Side Effects

  • Palpitation, fatigue, influenza-like symptoms
  • Dry mouth, taste disturbance, mouth ulcer, appetite and weight change
  • Atrial fibrillation, transient ischaemic attack, chest pain
  • Flushing, cough, dyspnoea, epistaxis
  • Anxiety, mental acuity impaired, paraesthesia, electrolyte disturbance, myalgia and arthralgia
  • Confusion and hallucinations (very rare)

Pregnancy & Lactation

  • Not recommended in women attempting to conceive
  • Excreted in the milk of lactating rats
  • Women who use the medication must not breastfeed

Precautions & Warnings

  • Caution is advised with treatment of patients most at risk of developing gastrointestinal complication with NSAIDs
  • Patients with significant risk factors for cardiovascular events should be treated with consideration
  • Caution in patients who have symptoms and/or signs suggesting liver dysfunction, or in whom an abnormal liver function test has occurred
  • Caution when co-administering with warfarin or other oral anticoagulants

Overdose Effects

  • Single doses up to 500 mg and multiple doses up to 150 mg/day did not result in significant toxicity
  • Usual supportive measures should be employed in the event of overdose

Therapeutic Class

Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

Store at a temperature of below 30°C, protect from light & moisture, Keep out of reach of children

Chemical Structure

  • Molecular Formula: C18H15ClN2O2S

Common Questions

  • Duration of effect of the medication
  • Onset of action
  • Pregnancy warnings
  • Habit forming tendencies
  • Breastfeeding warnings
  • Safety with alcohol
  • Safety to drive while on the medicine
  • Impact on kidney and liver function
  • Quick tips for using the medication

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